Nuclear factor erythroid 2-related factor (Nrf) 2 is a transcription factor that integrates cellular
stress signals by directing various transcriptional programs. As an evolutionarily conserved …

The gene expression program induced by NRF2 transcription factor plays a critical role in
cell defense responses against a broad variety of cellular stresses, most importantly …

Nuclear factor erythroid 2-related factor (Nrf2) is a transcriptional activator of the cell
protection gene that binds to the antioxidant response element (ARE). Therefore, Nrf2 …

Transcription factor nuclear factor erythroid 2‐related factor 2 (Nrf2) is a major regulator of
antioxidant response element‐(ARE‐) driven cytoprotective protein expression. The …

Mutations in the KEAP1–NRF2 (Kelch-like ECH-associated protein 1–nuclear factor-
erythroid 2 p45-related factor 2) pathway occur in up to a third of non–small cell lung cancer …

Nuclear factor, erythroid‐derived 2, like 2 (NRF2) is a key regulator of antioxidants and
cellular stress responses. The role of NRF2 in pulmonary neoplasia, a diverse disease for …

Abstract Transcription factor Nrf2 (NF-E2-related factor 2) is essential for oxidative and
electrophilic stress responses. While it has been well characterized that Nrf2 activity is tightly …

Nuclear factor erythroid 2-related factor 2 (Nrf2) is a major transcription factor involved in
redox homeostasis and in the response induced by oxidative injury. Nrf2 is present in an …

Nuclear factor, erythroid 2 related factor 2 (Nrf2) belongs to the Cap'n'collar/basic region
leucine zipper (CNC-bZIP) transcription factor family, and is activated by diverse oxidants …

Simple Summary Nuclear factor erythroid-derived 2-like 2 (encoded by the Nfe2l2 gene;
NRF2) is a transcription factor that regulates a variety of cytoprotective genes, including …