Mandarin translation of abstract Medicines that activate cannabinoid CB1 and CB2 receptor
are already in the clinic. These are Cesamet®(nabilone), Marinol®(dronabinol; Δ9 …

Human tissues express cannabinoid CB1 and CB2 receptors that can be activated by
endogenously released 'endocannabinoids' or exogenously administered compounds in a …

This review highlights some important advances that have taken place in cannabinoid
research over the last four years. It focuses on novel ligands that are of interest either as …

There are at least 2 types of cannabinoid receptor, CB 1 and CB 2, both G protein coupled.
CB 1 receptors are expressed predominantly at nerve terminals and mediate inhibition of …

ABSTRACT A major finding—that (–)‐trans‐Δ9‐tetrahydrocannabinol (Δ9‐THC) is largely
responsible for the psychotropic effects of cannabis—prompted research in the 1970s and …

Research into the pharmacology of individual cannabinoids that began in the 1940s, several
decades after the presence of a cannabinoid was first detected in cannabis, is concisely …

It is widely accepted that non-endogenous compounds that target CB1 and/or CB2 receptors
possess therapeutic potential for the clinical management of an ever growing number of …

The CB1 and CB2 cannabinoid receptors are members of the G protein-coupled receptor
(GPCR) family that are pharmacologically well defined. However, the discovery of additional …

Introduction 3. The cannabinoids: A brief history 3.1. Cannabinoids and the discovery of
cannabinoid receptors 3.2. Endocannabinoids 3.2. 1 Anandamide 3.2. 2 2-arachidonoyl …

▪ Abstract CB1 and CB2 cannabinoid receptors are the primary targets of endogenous
cannabinoids (endocannabinoids). These G protein–coupled receptors play an important …