Transition between Different Diffusion Modes of Individual Lipids during the Membrane‐Specific Action of As‐CATH4 Peptides
The cell membrane permeabilization ability of immune defense antimicrobial peptides
(AMPs) is widely applied in biomedicine. Although the mechanisms of peptide–membrane …
(AMPs) is widely applied in biomedicine. Although the mechanisms of peptide–membrane …
Diffusion as a probe of peptide-induced membrane domain formation
Recently, we have shown that association with an antimicrobial peptide (AMP) can
drastically alter the diffusion behavior of the constituent lipids in model membranes …
drastically alter the diffusion behavior of the constituent lipids in model membranes …
Quantified membrane permeabilization indicates the lipid selectivity of membrane-active antimicrobials
A Stulz, A Vogt, JS Saar, L Akil, K Lienkamp… - Langmuir, 2019 - ACS Publications
Most antimicrobial peptides (AMPs) and their synthetic mimics (SMAMPs) are thought to act
by permeabilizing cell membranes. For antimicrobial therapy, selectivity for pathogens over …
by permeabilizing cell membranes. For antimicrobial therapy, selectivity for pathogens over …
Diffusion as a Probe of the Heterogeneity of Antimicrobial Peptide− Membrane Interactions
Many antimicrobial peptides (AMPs) function by forming various oligomeric structures and/or
pores upon binding to bacterial membranes. Because such peptide aggregates are capable …
pores upon binding to bacterial membranes. Because such peptide aggregates are capable …
Current understanding of the mechanisms by which membrane-active peptides permeate and disrupt model lipid membranes
Three classes of membrane active peptides (MAPs) are considered in this review: cell
penetrating peptides (CPPs); anti-microbial peptides (AMPs), and amyloidal peptides. We …
penetrating peptides (CPPs); anti-microbial peptides (AMPs), and amyloidal peptides. We …
Membrane targeting cationic antimicrobial peptides
Many short cationic peptides are amphiphilic and are often termed antimicrobial peptides
(AMPs) as they can kill various microorganisms. These AMPs have largely been discovered …
(AMPs) as they can kill various microorganisms. These AMPs have largely been discovered …
Single-molecule resolution of antimicrobial peptide interactions with supported lipid a bilayers
N Nelson, DK Schwartz - Biophysical journal, 2018 - cell.com
The molecular interactions between antimicrobial peptides (AMPs) and lipid A-containing
supported lipid bilayers were probed using single-molecule total internal reflection …
supported lipid bilayers were probed using single-molecule total internal reflection …
[HTML][HTML] Beyond structural models for the mode of action: How natural antimicrobial peptides affect lipid transport
Hypothesis: Most textbook models for antimicrobial peptides (AMP) mode of action are
focused on structural effects and pore formation in lipid membranes, while these …
focused on structural effects and pore formation in lipid membranes, while these …
Cationic antimicrobial peptides: a physical basis for their selective membrane-disrupting activity
S Taheri-Araghi, BY Ha - Soft matter, 2010 - pubs.rsc.org
Antimicrobial peptides (AMPs) are not only fast microbe-killing molecules deployed in the
host defense of living organisms, but also offer valuable lessons for developing new …
host defense of living organisms, but also offer valuable lessons for developing new …
Antimicrobial peptides-interaction with membrane lipids and proteins
Antimicrobial peptides (AMPs) are a natural class of antibiotics that are present in all
domains of life (Hancock and Chapple, 1999). AMPs are part of the innate immune system …
domains of life (Hancock and Chapple, 1999). AMPs are part of the innate immune system …