Herein, we describe a general hydrodefunctionalization protocol of alcohols and amines
through a common isonitrile intermediate. To cleave the relatively inert C− NC bond, we …

We report here a reaction that selectively deaminates primary amines and anilines under
mild conditions and with remarkable functional group tolerance including a range of …

Herein, we report the use of isonitriles as alkyl radical precursors in light‐mediated hydro‐
and deuterodeamination reactions. The reaction is scalable, shows broad functional group …

Nitrene transfer reactions represent one of the key reactions to rapidly construct new carbon-
nitrogen bonds and typically require transition metal catalysts to control the reactivity of the …

N-Demethylation of trialkylamines is a useful transformation, but typically requires harsh
reaction conditions and stepwise procedures, as well as judicious protection of labile …

Nitriles and alkenes are important synthetic intermediates with complementary reactivity that
play a central role in the preparation of materials, pharmaceuticals, cosmetics, and …

β-Amino nitriles are important molecular scaffolds. Cyanoalkylation of imines is the most
straightforward method for the construction of these scaffolds. In this study, we report the …

Conspectus Because of the importance of nitrogen-containing compounds in chemistry and
biology, organic chemists have long focused on the development of novel methodologies for …

The utilization of N‐centered radicals to synthesize nitrogen‐containing compounds has
attracted considerable attention recently, due to their powerful reactivities and the …

The hydrocyanation of alkenes can be considered a straightforward methodology that gives
access to different functionalized organic chemistry entities. This is due to nitrile's high …