Clinical viability of boron neutron capture therapy for personalized radiation treatment

D Skwierawska, JA López-Valverde, M Balcerzyk… - Cancers, 2022 - mdpi.com
Simple Summary Usually, for dose planning in radiotherapy, the tumor is delimited as a
volume on the image of the patient together with other clinical considerations based on …

Importance of radiobiological studies for the advancement of boron neutron capture therapy (BNCT)

AM Hughes - Expert Reviews in Molecular Medicine, 2022 - cambridge.org
Boron neutron capture therapy (BNCT) is a tumour selective particle radiotherapy, based on
the administration of boron carriers incorporated preferentially by tumour cells, followed by …

Strategic Clinical Trial Design for Boron Neutron Capture Therapy

A Wittig, WAG Sauerwein - Cancer Biotherapy & …, 2023 - liebertpub.com
Boron neutron capture therapy (BNCT) involves infusion of cancer patients with a tumor-
seeking, boron-loaded compound and irradiation by a beam of neutrons, with an energy …

Boron neutron capture therapy: Moving toward targeted cancer therapy

HR Mirzaei, A Sahebkar, R Salehi… - Journal of cancer …, 2016 - journals.lww.com
Boron neutron capture therapy (BNCT) occurs when a stable isotope, boton-10, is irradiated
with low-energy thermal neutrons to yield stripped down helium-4 nuclei and lithium-7 …

'Close-to-ideal'tumor boron targeting for boron neutron capture therapy is possible with 'less-than-ideal'boron carriers approved for use in humans

AE Schwint, VA Trivillin - Therapeutic Delivery, 2015 - Future Science
Boron neutron capture therapy (BNCT) is classically described as a binary treatment
modality for cancer that involves the selective accumulation of boron carriers in tumors …

Accelerator-based boron neutron capture therapy facility at the Helsinki University Hospital

L Porra, T Seppälä, L Wendland, H Revitzer… - Acta …, 2022 - Taylor & Francis
Background Boron neutron capture therapy (BNCT) is a unique type of radiation therapy that
enables biological targeting of cancer at the cellular level. BNCT has been used to treat …

Optimizing boron neutron capture therapy (BNCT) to treat cancer: an updated review on the latest developments on boron compounds and strategies

A Monti Hughes, N Hu - Cancers, 2023 - mdpi.com
Simple Summary Boron neutron capture therapy (BNCT) is a tumor-selective particle
radiotherapy. It combines preferential boron accumulation in tumors and neutron irradiation …

[HTML][HTML] Boron neutron capture therapy: a review of clinical applications

TD Malouff, DS Seneviratne, DK Ebner… - Frontiers in …, 2021 - frontiersin.org
Boron neutron capture therapy (BNCT) is an emerging treatment modality aimed at
improving the therapeutic ratio for traditionally difficult to treat tumors. BNCT utilizes …

Theranostics in boron neutron capture therapy

WAG Sauerwein, L Sancey, E Hey-Hawkins, M Kellert… - Life, 2021 - mdpi.com
Boron neutron capture therapy (BNCT) has the potential to specifically destroy tumor cells
without damaging the tissues infiltrated by the tumor. BNCT is a binary treatment method …

[HTML][HTML] The role of radiolabeling in BNCT tracers for enhanced dosimetry and treatment planning

S Mushtaq, P Ji, JY Kim, KC Lee, KI Kim - Theranostics, 2023 - ncbi.nlm.nih.gov
Positron emission tomography (PET) and single photon emission computed tomography
(SPECT) are potent technologies for non-invasive imaging of pharmacological and …