The impact of glucose-lowering drugs on sarcopenia in type 2 diabetes: current evidence and underlying mechanisms

E Massimino, A Izzo, G Riccardi, G Della Pepa - Cells, 2021 - mdpi.com
The age-related decrease in skeletal muscle mass together with the loss of muscle power
and function is defined sarcopenia. Mounting evidence suggests that the prevalence of …

The impact of antidiabetic agents on sarcopenia in type 2 diabetes: a literature review

CN Wu, KJ Tien - Journal of diabetes research, 2020 - Wiley Online Library
Sarcopenia is a geriatric syndrome characterized by decline of skeletal muscle mass and
function. Contributing factors include nutritional, genetic, inflammatory, and endocrinal …

Anti‐diabetic drugs and sarcopenia: emerging links, mechanistic insights, and clinical implications

X Zhang, Y Zhao, S Chen… - Journal of cachexia …, 2021 - Wiley Online Library
Sarcopenia, characterized by loss of skeletal muscle mass, quality, and strength, has
become a common hallmark of ageing and many chronic diseases. Diabetes mellitus …

[PDF][PDF] Sarcopenia and chronic complications of type 2 diabetes mellitus

D Purnamasari, EN Tetrasiwi, GJ Kartiko… - Review of Diabetic …, 2022 - ingentaconnect.com
Sarcopenia, defined as the loss of skeletal muscle mass and strength and/or a decrease in
physical performance, is classically related to aging. However, chronic disease, including …

Repurposing Drugs for Diabetes Mellitus as Potential Pharmacological Treatments for Sarcopenia–A Narrative Review

MD Witham, A Granic, E Pearson, SM Robinson… - Drugs & Aging, 2023 - Springer
Sarcopenia, the age-related loss of muscle strength and mass or quality, is a common
condition with major adverse consequences. Although the pathophysiology is incompletely …

The association between sarcopenia and diabetes: from pathophysiology mechanism to therapeutic strategy

H Chen, X Huang, M Dong, S Wen… - … Syndrome and Obesity, 2023 - Taylor & Francis
Diabetes and sarcopenia are emerging as serious public health issues. Sarcopenia, an age-
related disorder characterized by loss of skeletal muscle mass and function, is recognized …

Sarcopenia and type 2 diabetes mellitus: a bidirectional relationship

J Mesinovic, A Zengin, B De Courten… - … syndrome and obesity …, 2019 - Taylor & Francis
The incidence and prevalence of metabolic and musculoskeletal diseases are increasing.
Type 2 diabetes mellitus (T2DM) is characterized by insulin resistance, inflammation …

Sarcopenia and diabetes: A detrimental liaison of advancing age

G Lisco, OE Disoteo, A De Tullio, V De Geronimo… - Nutrients, 2023 - mdpi.com
Sarcopenia is an age-related clinical complaint characterized by the progressive
deterioration of skeletal muscle mass and strength over time. Type 2 diabetes (T2D) is …

Diet, exercise, and pharmacotherapy for sarcopenia in people with diabetes

Y Hashimoto, F Takahashi, T Okamura, M Hamaguchi… - Metabolism, 2023 - Elsevier
Diabetes prevalence is increasing rapidly in older people, and sarcopenia is prevalent as a
novel complication, particularly in patients with type 2 diabetes mellitus (T2DM). Therefore …

[HTML][HTML] Glycemic control and insulin improve muscle mass and gait speed in type 2 diabetes: the MUSCLES-DM study

K Sugimoto, H Ikegami, Y Takata, T Katsuya… - Journal of the American …, 2021 - Elsevier
Objectives Type 2 diabetes is a risk factor for sarcopenia. Evidence on the prevention of
sarcopenia using blood glucose–lowering therapy is limited. We aimed to examine the …