Objective We aimed to provide an evidence-supported update of the ECCO-ESPGHAN
guideline on the medical management of paediatric Crohn's disease [CD]. Methods We …

Children and adolescents with Crohn's disease (CD) present often with a more complicated
disease course compared to adult patients. In addition, the potential impact of CD on growth …

Abstract Background & Aims We aim to provide guidance for medical treatment of luminal
Crohn's disease in children. Methods We performed a systematic search of publication …

Background Robust evaluation of induction therapies using both clinical and inflammatory
outcomes in pediatric Crohn's disease (CD) are sparse. We attempted to evaluate clinical …

Abstract Background and Aims Exclusive enteral nutrition [EEN] is recommended as a first-
line induction therapy for paediatric Crohn's disease [CD] although corticosteroids [CS] are …

Objective In newly diagnosed paediatric patients with moderate-to-severe Crohn's disease
(CD), infliximab (IFX) is initiated once exclusive enteral nutrition (EEN), corticosteroid and …

Objectives Treatment options for patients with Crohn disease (CD) have expanded, but the
use of some of these options in pediatric patients remains controversial. The authors …

Background & Aims Standard therapy for children newly diagnosed with Crohn's disease
(CD) includes early administration of immunomodulators after initial treatment with …

Objective: Assess long-term effects of maintenance infliximab therapy in children with
moderately-to-severely active Crohn's disease. Research design and methods: One …

Background & Aims A better understanding of prognostic factors within the heterogeneous
spectrum of pediatric Crohn's disease (CD) should improve patient management and reduce …