All HPV-negative head and neck cancers are not the same: Analysis of the TCGA dataset reveals that anatomical sites have distinct mutation, transcriptome, hypoxia …
Purpose Head and neck squamous cell carcinoma (HNSCC) affects various anatomical
sites, which often dictates whether the cancer is managed with primary surgery or radiation …
sites, which often dictates whether the cancer is managed with primary surgery or radiation …
HPV33+ HNSCC is associated with poor prognosis and has unique genomic and immunologic landscapes
K Chatfield-Reed, S Gui, WQ O'Neill, TN Teknos, Q Pan - Oral oncology, 2020 - Elsevier
Objective To determine the influence of high-risk HPV genotype on outcomes in HNSCC
patients. Materials and Methods This is a retrospective analysis of The Cancer Genome …
patients. Materials and Methods This is a retrospective analysis of The Cancer Genome …
Association of tumor site with the prognosis and immunogenomic landscape of human papillomavirus–related head and neck and cervical cancers
G Zhu, N Amin, ME Herberg, CA Maroun… - … –Head & Neck …, 2022 - jamanetwork.com
Importance Human papillomavirus (HPV)–positive status in patients with oropharyngeal
squamous cell carcinoma (OPSCC) is associated with improved survival compared with …
squamous cell carcinoma (OPSCC) is associated with improved survival compared with …
Integrative analysis of head and neck cancer identifies two biologically distinct HPV and three non-HPV subtypes
Purpose: Current classification of head and neck squamous cell carcinomas (HNSCC)
based on anatomic site and stage fails to capture biologic heterogeneity or adequately …
based on anatomic site and stage fails to capture biologic heterogeneity or adequately …
[HTML][HTML] Targeted next-generation sequencing of head and neck squamous cell carcinoma identifies novel genetic alterations in HPV+ and HPV-tumors
Background Human papillomavirus positive (HPV+) head and neck squamous cell
carcinoma (HNSCC) is an emerging disease, representing a distinct clinical and …
carcinoma (HNSCC) is an emerging disease, representing a distinct clinical and …
[HTML][HTML] Molecular landscape of head and neck cancer and implications for therapy
CS Farah - Annals of Translational Medicine, 2021 - ncbi.nlm.nih.gov
Head and neck squamous cell carcinomas (HNSCC) arising from the oral cavity, pharynx,
and larynx constitute the 6 th most common human cancer. Human papillomavirus (HPV) …
and larynx constitute the 6 th most common human cancer. Human papillomavirus (HPV) …
[HTML][HTML] Histoepigenetic analysis of HPV-and tobacco-associated head and neck cancer identifies both subtype-specific and common therapeutic targets despite …
Although head and neck squamous cell carcinoma (HNSCC) has in the past been largely
associated with tobacco use, human papillomavirus (HPV+) oropharynx cancer has in …
associated with tobacco use, human papillomavirus (HPV+) oropharynx cancer has in …
Mutation of chromatin regulators and focal hotspot alterations characterize human papillomavirus–positive oropharyngeal squamous cell carcinoma
Background Human papillomavirus (HPV)–associated oropharyngeal cancer is a disease
clinically and biologically distinct from smoking‐related head and neck squamous cell …
clinically and biologically distinct from smoking‐related head and neck squamous cell …
[HTML][HTML] Genotyping and characterization of HPV status, hypoxia, and radiosensitivity in 22 head and neck cancer cell lines
Simple Summary Cell lines are widely used for research, but even commonly used cell lines
may not be well characterized, making validation of published data and generalizing the …
may not be well characterized, making validation of published data and generalizing the …
Biological features of human papillomavirus-related head and neck cancers contributing to improved response
C Cleary, JE Leeman, DS Higginson, N Katabi… - Clinical Oncology, 2016 - Elsevier
Head and neck squamous cell carcinomas (HNSCC) are the sixth most common malignancy
globally, and an increasing proportion of oropharyngeal HNSCCs are associated with the …
globally, and an increasing proportion of oropharyngeal HNSCCs are associated with the …
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- tumor site cervical cancers
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- neck cancer molecular landscape
- immune response head and neck
- tumor site immunogenomic landscape
- tumor site human papillomavirus
- neck cancer implications for therapy
- human papillomavirus head and neck
- neck cancer therapeutic targets