HIV-1: fifteen proteins and an RNA

AD Frankel, JAT Young - Annual review of biochemistry, 1998 - annualreviews.org
Human immunodeficiency virus type 1 is a complex retrovirus encoding 15 distinct proteins.
Substantial progress has been made toward understanding the function of each protein, and …

[PDF][PDF] Molecular biology of the human immunodeficiency virus accessory proteins

RA Subbramanian, EA Cohen - Journal of virology, 1994 - Am Soc Microbiol
The human immunodeficiency virus (HIV) is the causative agent of AIDS. HIV belongs to a
unique virus family, the Retroviridae, a group of small, enveloped, positive-strand RNA …

Molecular biology of the human immunodeficiency virus type 1

WA Haseltine - The FASEB journal, 1991 - Wiley Online Library
The immunodeficiency virus type 1 is a complex retrovirus. In addition to genes that specify
the proteins of the virus particle and the replicative enzymes common to all retroviruses, HIV …

Structural biology of HIV

BG Turner, MF Summers - Journal of molecular biology, 1999 - Elsevier
The human immunodeficiency virus (HIV) genome encodes a total of three structural
proteins, two envelope proteins, three enzymes, and six accessory proteins. Studies over the …

[引用][C] Regulatory pathways governing HIV-1 replication

BR Cullen, WC Greene - Cell, 1989 - Elsevier
The lentiviruses are pathogenic retroviruses that induce chronic, degenerative diseases in
their animal hosts. This virus family is distinguished by a genomic structure that is the most …

The choreography of HIV-1 proteolytic processing and virion assembly

SK Lee, M Potempa, R Swanstrom - Journal of Biological Chemistry, 2012 - ASBMB
HIV-1 has been the target of intensive research at the molecular and biochemical levels for>
25 years. Collectively, this work has led to a detailed understanding of viral replication and …

[HTML][HTML] HIV-1 auxiliary proteins: making connections in a dying cell

BR Cullen - Cell, 1998 - cell.com
Shortly after the first molecular clones of human immunodeficiency virus type 1 (HIV-1) were
obtained, it became apparent that the genomic organization of this human retroviral …

Structure and function of the human immunodeficiency virus leader RNA

B Berkhout - Progress in nucleic acid research and molecular …, 1996 - Elsevier
Publisher Summary This chapter deals with the structure and function of the leader transcript
of human immunodeficiency virus (HIV-1) and HIV-2. Most of the RNA signals encoded by …

The structural biology of HIV-1: mechanistic and therapeutic insights

A Engelman, P Cherepanov - Nature Reviews Microbiology, 2012 - nature.com
Three-dimensional molecular structures can provide detailed information on biological
mechanisms and, for cases in which the molecular function affects human health, can …

Role of auxiliary proteins in retroviral morphogenesis

EA Cohen, RA Subbramanian… - … and Maturation of …, 1996 - Springer
Though both the oncoviruses and the lentiviruses belong to the Retroviridae family, the
lentiviral subfamily is comparatively complex both from the point of view of the number of …