Poly (amidoamine)(PAMAM) dendrimers: from biomimicry to drug delivery and biomedical applications

R Esfand, DA Tomalia - Drug discovery today, 2001 - Elsevier
Poly (amidoamine)(PAMAM) dendrimers are the first complete dendrimer family to be
synthesized, characterized and commercialized. Based on this extensive activity, they are …

Self-assembling supramolecular dendrimers for biomedical applications: Lessons learned from poly (amidoamine) dendrimers

Z Lyu, L Ding, A Tintaru, L Peng - Accounts of Chemical Research, 2020 - ACS Publications
Conspectus Dendrimers, notable for their well-defined radial structures with numerous
terminal functionalities, hold great promise for biomedical applications such as drug …

New advances in general biomedical applications of PAMAM dendrimers

RV Araújo, SS Santos, E Igne Ferreira, J Giarolla - Molecules, 2018 - mdpi.com
Dendrimers are nanoscopic compounds, which are monodispersed, and they are generally
considered as homogeneous. PAMAM (polyamidoamine) was introduced in 1985, by …

PAMAM dendrimer as a talented multifunctional biomimetic nanocarrier for cancer diagnosis and therapy

B Surekha, NS Kommana, SK Dubey… - Colloids and Surfaces B …, 2021 - Elsevier
Abstract Poly (amidoamine) dendrimers (PAMAM) are novel polymeric highly branched
architectures with well-defined nano-size, narrow polydispersity index and numerous active …

[HTML][HTML] Bioapplications of poly (amidoamine)(PAMAM) dendrimers in nanomedicine

N Taghavi Pourianazar, P Mutlu, U Gunduz - Journal of Nanoparticle …, 2014 - Springer
Abstract Poly (amidoamine)(PAMAM) dendrimers are a novel class of spherical, well-
designed branching polymers with interior cavities and abundant terminal groups on the …

Poly (amidoamine) dendrimers: Covalent and supramolecular synthesis

Z Lyu, L Ding, AYT Huang, CL Kao, L Peng - Materials Today Chemistry, 2019 - Elsevier
Dendrimers, a class of synthetic macromolecules which are notable for their well-defined
ramified structures and unique multivalent cooperativity, hold great promise for developing …

PAMAM dendrimers: destined for success or doomed to fail? Plain and modified PAMAM dendrimers in the context of biomedical applications

M Labieniec-Watala, C Watala - Journal of pharmaceutical sciences, 2015 - Elsevier
PAMAM (polyamidoamine) dendrimers are commonly considered promising polymers that
can be successfully used in various biomedical applications. Nevertheless, direct clinical …

PAMAM dendrimers as efficient drug and gene delivery nanosystems for cancer therapy

F Abedi-Gaballu, G Dehghan, M Ghaffari, R Yekta… - Applied materials …, 2018 - Elsevier
Drug delivery systems for cancer chemotherapy are employed to improve the effectiveness
and decrease the side-effects of highly toxic drugs. Most chemotherapy agents have …

Amino acid-functionalized dendrimers with heterobifunctional chemoselective peripheral groups for drug delivery applications

RS Navath, AR Menjoge, B Wang, R Romero… - …, 2010 - ACS Publications
Dendrimers have emerged as multifunctional carriers for targeted drug delivery, gene
delivery and imaging. Improving the functional versatility at the surface for carrying multiple …

Dendrimers:: Relationship between structure and biocompatibility in vitro, and preliminary studies on the biodistribution of 125I-labelled polyamidoamine dendrimers …

N Malik, R Wiwattanapatapee, R Klopsch… - Journal of Controlled …, 2000 - Elsevier
Dendrimers are highly branched macromolecules of low polydispersity that provide many
exciting opportunities for design of novel drug-carriers, gene delivery systems and imaging …