MyelStones: the executive roles of myelin basic protein in myelin assembly and destabilization in multiple sclerosis
KA Vassall, VV Bamm, G Harauz - Biochemical Journal, 2015 - portlandpress.com
The classic isoforms of myelin basic protein (MBP, 14–21.5 kDa) are essential to formation
of the multilamellar myelin sheath of the mammalian central nervous system (CNS). The …
of the multilamellar myelin sheath of the mammalian central nervous system (CNS). The …
Structural polymorphism and multifunctionality of myelin basic protein
G Harauz, V Ladizhansky, JM Boggs - Biochemistry, 2009 - ACS Publications
Central nervous system myelin is a dynamic entity arising from membrane processes
extended from oligodendrocytes, which form a tightly wrapped multilamellar structure …
extended from oligodendrocytes, which form a tightly wrapped multilamellar structure …
Classic 18.5-and 21.5-kDa myelin basic protein isoforms associate with cytoskeletal and SH3-domain proteins in the immortalized N19-oligodendroglial cell line …
GST Smith, L Homchaudhuri, JM Boggs… - Neurochemical …, 2012 - Springer
Abstract The 18.5-kDa classic myelin basic protein (MBP) is an intrinsically disordered
protein arising from the Golli (Genes of Oligodendrocyte Lineage) gene complex and is …
protein arising from the Golli (Genes of Oligodendrocyte Lineage) gene complex and is …
Myelin management by the 18.5‐kDa and 21.5‐kDa classic myelin basic protein isoforms
G Harauz, JM Boggs - Journal of neurochemistry, 2013 - Wiley Online Library
The classic myelin basic protein (MBP) splice isoforms range in nominal molecular mass
from 14 to 21.5 kDa, and arise from the gene in the oligodendrocyte lineage (Golli) in …
from 14 to 21.5 kDa, and arise from the gene in the oligodendrocyte lineage (Golli) in …
Molecular “negativity” may underlie multiple sclerosis: role of the myelin basic protein family in the pathogenesis of MS
AA Musse, G Harauz - International review of neurobiology, 2007 - Elsevier
Myelin basic protein (MBP) binds to negatively charged lipids on the cytosolic surface of
oligodendrocyte membranes and is responsible for adhesion of these surfaces in the …
oligodendrocyte membranes and is responsible for adhesion of these surfaces in the …
Myelin basic protein—diverse conformational states of an intrinsically unstructured protein and its roles in myelin assembly and multiple sclerosis
G Harauz, N Ishiyama, CMD Hill, IR Bates, DS Libich… - Micron, 2004 - Elsevier
The 18.5 kDa isoform of myelin basic protein (MBP) is a major component of the myelin
sheath in the central nervous system of higher vertebrates, and a member of a larger family …
sheath in the central nervous system of higher vertebrates, and a member of a larger family …
Myelin basic protein: a multifunctional protein
JM Boggs - Cellular and Molecular Life Sciences CMLS, 2006 - Springer
Myelin basic protein (MBP), the second most abundant protein in central nervous system
myelin, is responsible for adhesion of the cytosolic surfaces of multilayered compact myelin …
myelin, is responsible for adhesion of the cytosolic surfaces of multilayered compact myelin …
A tale of two citrullines—structural and functional aspects of myelin basic protein deimination in health and disease
G Harauz, AA Musse - Neurochemical research, 2007 - Springer
Myelin basic protein (MBP) binds to negatively charged lipids on the cytosolic surface of
oligodendrocyte membranes and is responsible for adhesion of these surfaces in the …
oligodendrocyte membranes and is responsible for adhesion of these surfaces in the …
Multiple sclerosis and myelin basic protein: Insights into protein disorder and disease
V Martinsen, P Kursula - Amino Acids, 2022 - Springer
Myelin basic protein (MBP) is an abundant protein in central nervous system (CNS) myelin.
MBP has long been studied as a factor in the pathogenesis of the autoimmune …
MBP has long been studied as a factor in the pathogenesis of the autoimmune …
The effects of threonine phosphorylation on the stability and dynamics of the central molecular switch region of 18.5-kDa myelin basic protein
KA Vassall, K Bessonov, M De Avila, E Polverini… - PloS one, 2013 - journals.plos.org
The classic isoforms of myelin basic protein (MBP) are essential for the formation and
maintenance of myelin in the central nervous system of higher vertebrates. The protein is …
maintenance of myelin in the central nervous system of higher vertebrates. The protein is …