[HTML][HTML] Cancer cachexia: molecular mechanisms and treatment strategies
T Setiawan, IN Sari, YT Wijaya, NM Julianto… - Journal of Hematology & …, 2023 - Springer
Muscle wasting is a consequence of physiological changes or a pathology characterized by
increased catabolic activity that leads to progressive loss of skeletal muscle mass and …
increased catabolic activity that leads to progressive loss of skeletal muscle mass and …
Advances in cancer cachexia: Intersection between affected organs, mediators, and pharmacological interventions
Advanced cancer patients exhibit cachexia, a condition characterized by a significant
reduction in the body weight predominantly from loss of skeletal muscle and adipose tissue …
reduction in the body weight predominantly from loss of skeletal muscle and adipose tissue …
Cancer cachexia: understanding the molecular basis
JM Argilés, S Busquets, B Stemmler… - Nature Reviews …, 2014 - nature.com
Cancer cachexia is a devastating, multifactorial and often irreversible syndrome that affects
around 50–80% of cancer patients, depending on the tumour type, and that leads to …
around 50–80% of cancer patients, depending on the tumour type, and that leads to …
Molecular pathways: cachexia signaling—a targeted approach to cancer treatment
Y Miyamoto, DL Hanna, W Zhang, H Baba… - Clinical Cancer Research, 2016 - AACR
Cancer cachexia is a multifactorial syndrome characterized by an ongoing loss of skeletal
muscle mass, which negatively affects quality of life and portends a poor prognosis …
muscle mass, which negatively affects quality of life and portends a poor prognosis …
[HTML][HTML] Molecular pathways leading to loss of skeletal muscle mass in cancer cachexia–can findings from animal models be translated to humans?
TC Mueller, J Bachmann, O Prokopchuk, H Friess… - BMC cancer, 2016 - Springer
Background Cachexia is a multi-factorial, systemic syndrome that especially affects patients
with cancer of the gastrointestinal tract, and leads to reduced treatment response, survival …
with cancer of the gastrointestinal tract, and leads to reduced treatment response, survival …
Understanding the mechanisms and treatment options in cancer cachexia
K Fearon, J Arends, V Baracos - Nature reviews Clinical oncology, 2013 - nature.com
Cancer cachexia is a metabolic syndrome that can be present even in the absence of weight
loss ('precachexia'). Cachexia is often compounded by pre-existing muscle loss, and is …
loss ('precachexia'). Cachexia is often compounded by pre-existing muscle loss, and is …
Cancer-induced muscle wasting: latest findings in prevention and treatment
Z Aversa, P Costelli… - Therapeutic advances in …, 2017 - journals.sagepub.com
Cancer cachexia is a severe and disabling clinical condition that frequently accompanies
the development of many types of cancer. Muscle wasting is the hallmark of cancer cachexia …
the development of many types of cancer. Muscle wasting is the hallmark of cancer cachexia …
[HTML][HTML] Cancer cachexia: mediators, signaling, and metabolic pathways
KCH Fearon, DJ Glass, DC Guttridge - Cell metabolism, 2012 - cell.com
Cancer cachexia is characterized by a significant reduction in body weight resulting
predominantly from loss of adipose tissue and skeletal muscle. Cachexia causes reduced …
predominantly from loss of adipose tissue and skeletal muscle. Cachexia causes reduced …
[HTML][HTML] Management of cancer cachexia: attempting to develop new pharmacological agents for new effective therapeutic options
GP Marceca, P Londhe, F Calore - Frontiers in oncology, 2020 - frontiersin.org
Cancer cachexia (CC) is a multifactorial syndrome characterized by systemic inflammation,
uncontrolled weight loss and dramatic metabolic alterations. This includes myofibrillar …
uncontrolled weight loss and dramatic metabolic alterations. This includes myofibrillar …
Cancer-mediated muscle cachexia: etiology and clinical management
T Siff, P Parajuli, MS Razzaque, A Atfi - Trends in Endocrinology & …, 2021 - cell.com
Muscle cachexia has a major detrimental impact on cancer patients, being responsible for
30% of all cancer deaths. It is characterized by a debilitating loss in muscle mass and …
30% of all cancer deaths. It is characterized by a debilitating loss in muscle mass and …
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