Blood miR-144-3p: a novel diagnostic and therapeutic tool for depression

YY van der Zee, LMT Eijssen, P Mews… - Molecular …, 2022 - nature.com
Major depressive disorder (MDD) is the leading cause of disability worldwide. There is an
urgent need for objective biomarkers to diagnose this highly heterogeneous syndrome …

Identification of microRNA-124-3p as a putative epigenetic signature of major depressive disorder

B Roy, M Dunbar, RC Shelton, Y Dwivedi - Neuropsychopharmacology, 2017 - nature.com
Major depressive disorder (MDD) is predicted to be the second leading cause of global
disease burden by 2030. A large number of MDD patients do not respond to the currently …

Peripheral whole blood microRNA alterations in major depression and bipolar disorder

E Maffioletti, A Cattaneo, G Rosso, G Maina… - Journal of affective …, 2016 - Elsevier
Major depression (MD) and bipolar disorder (BD) are severe and potentially life-threating
mood disorders whose etiology is to date not completely understood. MicroRNAs (miRNAs) …

Emerging role of microRNAs in major depressive disorder: diagnosis and therapeutic implications

Y Dwivedi - Dialogues in clinical neuroscience, 2014 - Taylor & Francis
Major depressive disorder (MDD) is a major public health concern. Despite tremendous
advances, the pathogenic mechanisms associated with MDD are still unclear. Moreover, a …

Emerging role of microRNAs in major depressive disorder and its implication on diagnosis and therapeutic response

L Zhou, Y Zhu, W Chen, Y Tang - Journal of Affective Disorders, 2021 - Elsevier
Background: Major depressive disorder (MDD) is a serious and common psychiatric
disorder with a high prevalence in the population. Although great advances have been …

Major depression and its treatment: microRNAs as peripheral biomarkers of diagnosis and treatment response

JP Lopez, A Kos, G Turecki - Current opinion in psychiatry, 2018 - journals.lww.com
In this review, we discuss the growing field, investigating peripheral miRNAs as potential
biomarkers of major depression and treatment response. A noninvasive and validated …

Differential expression of microRNA in peripheral blood mononuclear cells as specific biomarker for major depressive disorder patients

H Fan, X Sun, W Guo, A Zhong, W Niu, L Zhao… - Journal of psychiatric …, 2014 - Elsevier
Currently, diagnosis and treatment of major depressive disorder (MDD) are based on the
patients' description of symptoms, mental status examinations, and clinical behavioral …

MicroRNA as therapeutic targets for treatment of depression

KF Hansen, K Obrietan - Neuropsychiatric Disease and Treatment, 2013 - Taylor & Francis
Depression is a potentially life-threatening mental disorder affecting approximately 300
million people worldwide. Despite much effort, the molecular underpinnings of clinical …

MicroRNA-based biomarkers in the diagnosis and monitoring of therapeutic response in patients with depression

YY Xu, QH Xia, QR Xia, XL Zhang… - … disease and treatment, 2019 - Taylor & Francis
Depression is a debilitating mental illness that affects up to 120 million people worldwide; it
is currently determined based on subjective diagnostic schemes that are limited by high …

Combining inflammatory miRNA molecules as diagnostic biomarkers for depression: a clinical study

JP Brás, S Pinto, O von Doellinger, J Prata… - Frontiers in …, 2023 - frontiersin.org
Background Inflammation has been implicated in core features of depression
pathophysiology and treatment resistance. Therefore, new challenges in the discovery of …