Uric acid (UA) is the end product of purine metabolism and can reportedly act as an
antioxidant. However, recently, numerous clinical and basic research approaches have …

Hyperuricemia is a common metabolic syndrome. Elevated uric acid levels are risk factors
for gout, hypertension, and chronic kidney diseases. Furthermore, various epidemiological …

Serum uric acid (SUA) is significantly elevated in obesity, gout, type 2 diabetes mellitus, and
the metabolic syndrome and appears to contribute to the renal, cardiovascular and …

Uric acid is the end product of purine metabolism. Its immediate precursor, xanthine, is
converted to uric acid by an enzymatic reaction involving xanthine oxidoreductase. Uric acid …

Hyperuricemia is known to be associated with the presence of cardiovascular and metabolic
syndrome and with the development of incipient kidney disease and an accelerated renal …

Hyperuricemia is caused by reduced renal/extrarenal excretion and overproduction of uric
acid. It is affected by genetic predisposition related to uric acid transporters and by visceral …

As an end product of purine metabolism, uric acid (UA) is a major endogenous antioxidant in
humans. However, impaired UA synthesis and excretion can lead to hyperuricemia (HUA) …

Hyperuricemia, which has been considered as a cause of gout and nephrolithiasis has
recently been suggested to be associated with hypertension, coronary heart disease, heart …

Uric acid (UA) is the end product of purine nucleotide metabolism in the human body.
Hyperuricemia is an abnormally high level of UA in the blood and may result in arthritis and …

Uric acid is the end product of purine metabolism catalyzed by xanthine oxidase in humans.
In the process of purine metabolism, reactive oxygen species, including superoxide, are …