With the aim to establish a structure-inhibitory activity relationship of flavonoids against
dipeptidyl peptidase-4 (DPP-4) and elucidate the interaction mechanisms between them, a …

The inhibitory effects of 30 dietary flavonoids on dipeptidyl peptidase-IV (DPP-IV) were
investigated to illustrate their quantitative structure–activity relationship (QSAR) and further …

Dipeptidyl peptidase-4 (DPP-4) inhibitors present a unique approach for the management of
type 2 diabetes (T2D). In the present study, the inhibition of DPP-4 was evaluated for a large …

Type 2 diabetes mellitus (T2DM) is a growing global public health issue, and dipeptidyl
peptidase-4 (DPP-4) is a potential therapeutic target in T2DM. Several synthetic anti-DPP-4 …

Dipeptidyl peptidase IV (DPP-IV), a new target for the treatment of type 2 diabetes mellitus,
degrades incretins such as glucagon-like peptide 1 (GLP-1) and glucose-dependent …

Beneficial health effects of fruits and vegetables in the diet have been attributed to their high
flavonoid content. Dipeptidyl peptidase IV (DPP‐IV) is a serine aminopeptidase that is a …

Dietary polyphenols with great antidiabetic effects are the most abundant components in
edible products. Dietary polyphenols have attracted attention as dipeptidyl peptidase-IV …

Numerous studies indicate that diets with a variety of fruits and vegetables decrease the
incidence of severe diseases, like diabetes, obesity, and cancer. Diets contain a variety of …

This study compared dipeptidyl peptidase-4 (DPP-4) inhibitory activity of citrus bioflavonoid
nutraceuticals compared with three gliptins. Citrus bioflavonoid standards and three …

Abstract Dipeptidyl peptidase 4 (DPP-4) inhibitors are used for the treatment of type-2
diabetes mellitus. Various synthetic inhibitors have been developed to date, and plants …