Molecular interaction of centella asiatica bioactive compounds and Donepezil on alzheimer's protein through in silico studies

HA Marzouk, S Wibowo, H Khotimah… - Research Journal of …, 2022 - indianjournals.com
Alzheimer's disease is a chronic neurodegenerative illness that is one of the most persistent
medical concerns with significant social and economic consequences. Current treatments …

In-Silico and In-Vitro correlation studies of natural β-secretase inhibitor: An approach towards Alzheimer's Disease

V Pai, KS Chandrashekar… - Research Journal of …, 2017 - indianjournals.com
Alzheimer's disease (AD) is one among the common type of dementia in elder people above
the age group of 65 years. This was once considered a rare disorder but in recently was …

In Silico Investigation of Novel Compounds as Inhibitors of Acetylcholinesterase Enzyme for the Treatment of Alzheimer's Diseases

K Adebambo, O Ojoh - International Journal of Alzheimer's …, 2024 - Wiley Online Library
Alzheimer's disease (AD) is a “progressive, neurodegenerative disease that occurs when
nerve cells in the brain die.” There are only 4 drugs approved by the United States Food and …

[PDF][PDF] In silico investigation of flavanone compounds' inhibitory effects on alpha-amylase enzyme and predicting their inhibitory role in diabetes progression

M Sadeghi, M Miroliaei, Z Shorakai - Journal of Fasa University of …, 2020 - jabs.fums.ac.ir
Background & Objective: Diabetes is one of the most common metabolic disorders. Alpha-
amylase plays an important role in the development of diabetes by breaking down …

[PDF][PDF] Quercetin Compound Analysis to Develop Treatment for Dementia Associated with Alzheimer? s disease in Humans: Insilico Study

A Joshi, N Vats, H Singh, V Kaushik - Journal of Drug and Alcohol …, 2022 - researchgate.net
Background: Alzheimer's disease is a memory loss problem associated mostly with elderly
people, the cause of this disease is generally accumulation of beta-amyloid plaques around …

Molecular Docking and In Silico ADMET Study Reveals Acylguanidine 7a as a Potential Inhibitor of β‐Secretase

CM Nisha, A Kumar, P Nair, N Gupta… - Advances in …, 2016 - Wiley Online Library
Amyloidogenic pathway in Alzheimer's disease (AD) involves breakdown of APP by β‐
secretase followed by γ‐secretase and results in formation of amyloid beta plaque. β …

In silico identification of novel apolipoprotein e4 inhibitor for alzheimer's disease therapy

S Bano, MA Rasheed, F Jamil… - … Computer-Aided Drug …, 2019 - ingentaconnect.com
Introduction: Apolipoprotein E4 (ApoE) is a major genetic factor for developing Alzheimer's
disease (AD). It plays a vital role in brain to maintain a constant supply of neuronal lipids for …

[HTML][HTML] Curcumin analogues as promissory compounds for inhibition of β-secretase, γ-secretase and GSK-3β implicated at Alzheimer disease: in silico study

N Contreras-Puentes… - Biomedical and …, 2022 - biomedpharmajournal.org
Aims: Alzheimer's disease is a disorder associated to dementia that widely affects to
population. In the molecular study, key enzymes have been associated with the regulation of …

[PDF][PDF] In silico study of Centella asiatica active compound as BACE1 inhibitor in Alzheimer's disease

N Mawaddani, NRK Wibowo… - J Smart …, 2020 - download.garuda.kemdikbud.go.id
Alzheimer (AD) is a chronical neurodegenerative disease which is the 6th leading cause of
death worldwide. About 36 million cases in the world and may increase to 115 million in …