Recurrent abnormalities can be used for risk group stratification in pediatric AMKL: a retrospective intergroup study
JDE De Rooij, R Masetti… - Blood, The Journal …, 2016 - ashpublications.org
Genetic abnormalities and early treatment response are the main prognostic factors in acute
myeloid leukemia (AML). Acute megakaryoblastic leukemia (AMKL) is a rare subtype of …
myeloid leukemia (AML). Acute megakaryoblastic leukemia (AMKL) is a rare subtype of …
Pathologic, cytogenetic, and molecular features of acute myeloid leukemia with megakaryocytic differentiation: A report from the Children's Oncology Group
KM Chisholm, J Smith… - Pediatric blood & …, 2023 - Wiley Online Library
Background Acute myeloid leukemia (AML) with megakaryocytic differentiation (AMkL) is a
rare subtype of AML more common in children. Recent literature has identified multiple …
rare subtype of AML more common in children. Recent literature has identified multiple …
Pediatric non–Down syndrome acute megakaryoblastic leukemia is characterized by distinct genomic subsets with varying outcomes
JDE De Rooij, C Branstetter, J Ma, Y Li, MP Walsh… - Nature …, 2017 - nature.com
Acute megakaryoblastic leukemia (AMKL) is a subtype of acute myeloid leukemia (AML) in
which cells morphologically resemble abnormal megakaryoblasts. While rare in adults …
which cells morphologically resemble abnormal megakaryoblasts. While rare in adults …
Acute megakaryoblastic leukaemia (AMKL) in children: a comparison of AMKL with and without Down syndrome
A Hama, H Yagasaki, Y Takahashi… - British journal of …, 2008 - Wiley Online Library
To characterize childhood acute megakaryoblastic leukaemia (AMKL), we reviewed 45
children with AMKL diagnosed between 1986 and 2005 at Nagoya University Hospital and …
children with AMKL diagnosed between 1986 and 2005 at Nagoya University Hospital and …
Prognostic impact of specific molecular profiles in pediatric acute megakaryoblastic leukemia in non‐Down syndrome
Y Hara, N Shiba, K Ohki, K Tabuchi… - Genes …, 2017 - Wiley Online Library
Pediatric acute megakaryoblastic leukemia in non‐Down syndrome (AMKL) is a unique
subtype of acute myeloid leukemia (AML). Novel CBFA2T3‐GLIS2 and NUP98‐KDM5A …
subtype of acute myeloid leukemia (AML). Novel CBFA2T3‐GLIS2 and NUP98‐KDM5A …
Heterogeneous cytogenetic subgroups and outcomes in childhood acute megakaryoblastic leukemia: a retrospective international study
H Inaba, Y Zhou, O Abla, S Adachi… - Blood, The Journal …, 2015 - ashpublications.org
Comprehensive clinical studies of patients with acute megakaryoblastic leukemia (AMKL)
are lacking. We performed an international retrospective study on 490 patients (age≤ 18 …
are lacking. We performed an international retrospective study on 490 patients (age≤ 18 …
Improved outcome of pediatric patients with acute megakaryoblastic leukemia in the AML-BFM 04 trial
J Schweitzer, M Zimmermann, M Rasche… - Annals of …, 2015 - Springer
Despite recent advances in the treatment of children with acute megakaryoblastic leukemia
(AMKL) using intensified treatment protocols, clear prognostic indicators, and treatment …
(AMKL) using intensified treatment protocols, clear prognostic indicators, and treatment …
The changing scenario of non-Down syndrome acute megakaryoblastic leukemia in children
R Masetti, V Guidi, L Ronchini, NS Bertuccio… - Critical reviews in …, 2019 - Elsevier
Pediatric non-Down-syndrome acute megakaryoblastic leukemia (non-DS-AMKL) is a
heterogeneous subtype of leukemia that has historically been associated with poor …
heterogeneous subtype of leukemia that has historically been associated with poor …
NUP98/JARID1A is a novel recurrent abnormality in pediatric acute megakaryoblastic leukemia with a distinct HOX gene expression pattern
JDE de Rooij, IHIM Hollink, S Arentsen-Peters… - Leukemia, 2013 - nature.com
Cytogenetic abnormalities and early response to treatment are the main prognostic factors in
acute myeloid leukemia (AML). Recently, NUP98/NSD1 (t (5; 11)(q35; p15)), a …
acute myeloid leukemia (AML). Recently, NUP98/NSD1 (t (5; 11)(q35; p15)), a …
NUP98‐BPTF gene fusion identified in primary refractory acute megakaryoblastic leukemia of infancy
M Roussy, M Bilodeau, L Jouan… - Genes …, 2018 - Wiley Online Library
The advent of large scale genomic sequencing technologies significantly improved the
molecular classification of acute megakaryoblastic leukaemia (AMKL). AMKL represents a …
molecular classification of acute megakaryoblastic leukaemia (AMKL). AMKL represents a …