Genotype imputation is commonly performed in genome-wide association studies because it
greatly increases the number of markers that can be tested for association with a trait. In …

Genotype imputation has become a standard tool in genome-wide association studies
because it enables researchers to inexpensively approximate whole-genome sequence …

Genotype imputation is a statistical technique that is often used to increase the power and
resolution of genetic association studies. Imputation methods work by using haplotype …

Background Although high-throughput genotyping arrays have made whole-genome
association studies (WGAS) feasible, only a small proportion of SNPs in the human genome …

Genotype imputation methods are now being widely used in the analysis of genome-wide
association studies. Most imputation analyses to date have used the HapMap as a reference …

Genotype imputation is a process of estimating missing ge-notypes from the haplotype or
genotype reference panel. It can effectively boost the power of detecting single nucleotide …

Genotype imputation is a key step in the analysis of genome-wide association studies.
Upcoming very large reference panels, such as those from The 1000 Genomes Project and …

Imputation in admixed populations is an important problem but challenging due to the
complex linkage disequilibrium (LD) pattern. The emergence of large reference panels such …

Abstract The 1000 Genomes Project and disease-specific sequencing efforts are producing
large collections of haplotypes that can be used as reference panels for genotype imputation …

The utility of genotype imputation in genome-wide association studies is increasing as
progressively larger reference panels are improved and expanded through whole-genome …