[HTML][HTML] Targeting HMGB1: A potential therapeutic strategy for chronic kidney disease

T Liu, Q Li, Q Jin, L Yang, H Mao, P Qu… - … Journal of Biological …, 2023 - ncbi.nlm.nih.gov
High-mobility group protein box 1 (HMGB1) is a member of a highly conserved high-mobility
group protein present in all cell types. HMGB1 plays multiple roles both inside and outside …

HMGB1 in kidney diseases

Z Zhao, Z Hu, R Zeng, Y Yao - Life sciences, 2020 - Elsevier
High mobility group box 1 (HMGB1) is a highly conserved nucleoprotein involving in
numerous biological processes, and well known to trigger immune responses as the …

High mobility group box 1 and kidney diseases

P Zhu, L Xie, HS Ding, Q Gong… - International …, 2013 - spandidos-publications.com
High mobility group box 1 (HMGB1), a non-histone DNA-binding protein, regulates
nucleosome function and transcription in the nuclei of all metazoans and plants. However …

[HTML][HTML] The role of high mobility group box 1 (HMGB1) in the pathogenesis of kidney diseases

Q Chen, X Guan, X Zuo, J Wang, W Yin - Acta Pharmaceutica Sinica B, 2016 - Elsevier
High mobility group box 1 (HMGB1) is a nuclear protein that can bind to DNA and act as a co-
factor for gene transcription. When released into extracellular fluid, it plays a …

High mobility group box protein-1 correlates with renal function in chronic kidney disease (CKD)

A Bruchfeld, AR Qureshi, B Lindholm, P Barany… - Molecular …, 2008 - Springer
Chronic kidney disease (CKD) is associated with inflammation and malnutrition and carries
a markedly increased risk of cardiovascular disease (CVD). High Mobility Group Box Protein …

Emerging role of HMGB 1 in fibrotic diseases

LC Li, J Gao, J Li - Journal of cellular and molecular medicine, 2014 - Wiley Online Library
High‐mobility group box 1 (HMGB1) is originally identified as a DNA‐binding protein that
functions as a structural co‐factor critical for proper transcriptional regulation in somatic …

HMGB1 in systemic lupus erythematosus

T Liu, M Son, B Diamond - Frontiers in immunology, 2020 - frontiersin.org
The high-mobility group box 1 (HMGB1) has been shown to exert proinflammatory effects on
many cells of the innate immune system. Originally identified as a nuclear protein, HMGB1 …

High-mobility group box 1 protein (HMGB1) in ischaemic heart disease: beneficial or deleterious?

M Takahashi - Cardiovascular research, 2008 - academic.oup.com
High-mobility group box 1 (HMGB1; also known as amphoterin) protein was identified more
than 30 years ago as a non-chromosomal nuclear protein that maintains the nucleosome …

Oxidative stress-mediated HMGB1 biology

Y Yu, D Tang, R Kang - Frontiers in physiology, 2015 - frontiersin.org
High mobility group box 1 (HMGB1) is a widely-expressed and highly-abundant protein that
acts as an extracellular signal upon active secretion by immune cells or passive release by …

The effect and regulatory mechanism of high mobility group box-1 protein on immune cells in inflammatory diseases

Y Ge, M Huang, Y Yao - Cells, 2021 - mdpi.com
High mobility group box-1 protein (HMGB1), a member of the high mobility group protein
superfamily, is an abundant and ubiquitously expressed nuclear protein. Intracellular …