Genetic variation and exercise-induced muscle damage: implications for athletic performance, injury and ageing

P Baumert, MJ Lake, CE Stewart, B Drust… - European journal of …, 2016 - Springer
Prolonged unaccustomed exercise involving muscle lengthening (eccentric) actions can
result in ultrastructural muscle disruption, impaired excitation–contraction coupling …

[HTML][HTML] Pathophysiology of exercise-induced muscle damage and its structural, functional, metabolic, and clinical consequences

A Stožer, P Vodopivc, LK Bombek - Physiological research, 2020 - ncbi.nlm.nih.gov
Extreme or unaccustomed eccentric exercise can cause exercise-induced muscle damage,
characterized by structural changes involving sarcomere, cytoskeletal, and membrane …

Does exercise-induced muscle damage play a role in skeletal muscle hypertrophy?

BJ Schoenfeld - The Journal of Strength & Conditioning Research, 2012 - journals.lww.com
Schoenfeld, BJ. Does exercise-induced muscle damage play a role in skeletal muscle
hypertrophy? J Strength Cond Res 26 (5): 1441–1453, 2012—Exercise-induced muscle …

More than a 'speed gene': ACTN3 R577X genotype, trainability, muscle damage, and the risk for injuries

J Del Coso, D Hiam, P Houweling, LM Pérez… - European journal of …, 2019 - Springer
A common null polymorphism (rs1815739; R577X) in the gene that codes for α-actinin-3
(ACTN3) has been related to different aspects of exercise performance. Individuals who are …

ACTN3 and MLCK genotype associations with exertional muscle damage

PM Clarkson, EP Hoffman… - Journal of Applied …, 2005 - journals.physiology.org
Strenuous exercise results in damage to skeletal muscle that is manifested in delayed
muscle pain, prolonged strength loss, and increases in muscle proteins in the blood …

Skeletal muscle adaptations with age, inactivity, and therapeutic exercise

LDV Thompson - Journal of Orthopaedic & Sports Physical Therapy, 2002 - jospt.org
One of the remarkable features of skeletal muscle is its adaptability. Skeletal muscle
adaptations are characterized by modifications of morphological, biochemical, and …

Skeletal muscle damage with exercise and aging

GL Close, A Kayani, A Vasilaki, A McArdle - Sports medicine, 2005 - Springer
Skeletal muscle comprises the largest organ system in the human body and is essential for
force generation and movement. Skeletal muscle is subjected to considerable stresses …

Muscle damage and muscle remodeling: no pain, no gain?

KL Flann, PC LaStayo, DA McClain… - Journal of …, 2011 - journals.biologists.com
Skeletal muscle is a dynamic tissue that responds adaptively to both the nature and intensity
of muscle use. This phenotypic plasticity ensures that muscle structure is linked to patterns of …

[HTML][HTML] The genetics of sports injuries and athletic performance

N Maffulli, K Margiotti, UG Longo… - … and tendons journal, 2013 - ncbi.nlm.nih.gov
Purpose: in the last two decades, several evidences have been provided to support the
relationship between single nucleotide polymorphisms and the susceptibility to develop …

Lengthening our perspective: morphological, cellular, and molecular responses to eccentric exercise

RD Hyldahl, MJ Hubal - Muscle & nerve, 2014 - Wiley Online Library
The response of skeletal muscle to unaccustomed eccentric exercise has been studied
widely, yet it is incompletely understood. This review is intended to provide an up‐to‐date …