Pulmonary surfactant: A mighty thin film

F Possmayer, YY Zuo, RAW Veldhuizen… - Chemical …, 2023 - ACS Publications
Pulmonary surfactant is a critical component of lung function in healthy individuals. It
functions in part by lowering surface tension in the alveoli, thereby allowing for breathing …

Understanding the principle biophysics concepts of pulmonary surfactant in health and disease

C Autilio, J Pérez-Gil - Archives of Disease in Childhood-Fetal and …, 2019 - fn.bmj.com
Pulmonary surfactant (PS) is a lipid-protein complex essential to stabilise the delicate
structure of mammalian alveoli along with successive compression-expansion respiratory …

The biophysical function of pulmonary surfactant

S Rugonyi, SC Biswas, SB Hall - Respiratory physiology & neurobiology, 2008 - Elsevier
Pulmonary surfactant lowers surface tension in the lungs. Physiological studies indicate two
key aspects of this function: that the surfactant film forms rapidly; and that when compressed …

Biophysical behavior of lung surfactant: implications for respiratory physiology and pathophysiology.

RH Notter - Seminars in perinatology, 1988 - europepmc.org
The major emphasis of this article has been the complex, multicomponent system of
surfactants that are required for proper pulmonary mechanics and function in the …

Composition, structure and mechanical properties define performance of pulmonary surfactant membranes and films

E Parra, J Pérez-Gil - Chemistry and physics of lipids, 2015 - Elsevier
The respiratory surface in the mammalian lung is stabilized by pulmonary surfactant, a
membrane-based system composed of multiple lipids and specific proteins, the primary …

Molecular interactions in pulmonary surfactant films

J Pérez-Gil - Neonatology, 2002 - karger.com
Pulmonary surfactant is a lipid-protein complex which has the essential physiological role of
stabilizing the respiratory surface of lungs against collapse. To achieve this function …

Pulmonary surfactant: an interdisciplinary approach

RH Notter, JN Finkelstein - Journal of Applied Physiology, 1984 - journals.physiology.org
Pulmonary surfactant research is considered from the perspective of interdisciplinary
correlations based on information acquired from biophysics and physical chemistry …

Pulmonary surfactant: phase behavior and function

B Piknova, V Schram, SB Hall - Current opinion in structural biology, 2002 - Elsevier
Pulmonary surfactant functions by first flowing rapidly into the alveolar air/water interface, but
then resisting collapse from the surface when the adsorbed interfacial film is compressed …

Pulmonary surfactant-update on function, molecular biology and clinical implications

J Floros, DS Phelps, U Pison… - Current Respiratory …, 2005 - ingentaconnect.com
This review is based on the contents of an international congress entitled,“Surfactant 2004”,
organized by Drs. B. Lachmann and LMG van Golde and held in Berlin, Germany. This is the …

Pulmonary surfactant in health and human lung diseases: state of the art

M Griese - European Respiratory Journal, 1999 - Eur Respiratory Soc
Pulmonary surfactant is a complex and highly surface active material composed of lipids and
proteins which is found in the fluid lining the alveolar surface of the lungs. Surfactant …