We recently reported the potential application of recombinant prothrombin activator ecarin
(RAPClot™) in blood diagnostics. In a new study, we describe RAPClot™ as an additive to …

We describe here the purification and cloning of a codon-optimized form of the snake
prothrombin activator ecarin from the saw scaled viper (Echis carinatus) expressed in …

Background Incomplete blood clotting or latent clotting in serum is a common laboratory
problem, especially for patients on anticoagulant therapy or when serum tubes are …

The snake venom protease ecarin from Echis carinatus was expressed in stable transfected
CHO-S cells grown in animal component free cell culture medium. Recombinant ecarin (r …

Ecarin clotting time (ECT) is currently developed for the specific monitoring of antithrombin
drugs, such as hirudin, argatroban, and hirulog. Aqueous reagent and dry chemistry …

Assay conditions of a plasma-based ecarin clotting time (ECT) were evaluated and the
precision of the ECT in monitoring plasma levels of r-hirudin assessed. The snake venom …

Background: Current commercial tubes have difficulties in producing “true” serum from all
blood samples even within the recommended clotting times. Hence, Becton Dickinson (BD) …

A new sensitive and precise method for quantitative determination of direct thrombin
inhibitors is described, the ecarin chromogenic assay (ECA). Ecarin is used as the specific …

Original articles Page 1 https://doi.org/10.11613/BM.2019.030706 Biochem Med (Zagreb)
2019;29(3):030706 1 Abstract Introduction: Failure to obtain complete blood clotting in serum is …

Recently, low-dose hirudin has been suggested for the prevention of deep venous
thrombosis (DVT) after orthopaedic surgery in high-risk patients [1]. Monitoring of …