Helminth-modulated macrophages contribute to attenuating inflammation in inflammatory
bowel diseases. The programmed death 1 (PD-1) plays an important role in macrophage …

Background Many evidences show the inverse correlation between helminth infection and
allergic or autoimmune diseases. Identification and characterization of the active helminth …

Helminth infection induces Th2-biased immune responses and inhibitory/regulatory
pathways that minimize excessive inflammation to facilitate the chronic infection of helminth …

Trichinella spiralis is a zoonotic nematode and food borne parasite and infection with T.
spiralis leads to suppression of the host immune response and other immunopathologies …

Extracellular vesicles (EVs) are membranous containers released by cells that are powerful
agents of intercellular communication. EVs have been described for various parasites and …

Background Therapeutic potential of helminth have been shown to have a protective effect
on immune-mediated diseases such as Crohn's disease (CD), which is associated with …

Chronic inflammation of the intestinal mucosa is characteristic of inflammatory bowel
diseases such as ulcerative colitis and Crohn's disease. Helminth parasites have developed …

Inflammatory bowel diseases (IBDs) have been classified as modern refractory diseases.
However, safe, well-tolerated, and effective treatments for IBDs are still lacking. Therefore …

Helminths and their products can suppress the host immune response and other
immunopathologies which may benefit parasite survival. Parasitic nematode Trichinella …

Trichinella spiralis is a zoonotic nematode and food borne parasite and infection with T.
spiralis leads to suppression of the host immune response and other immunopathologies …