Glycointeractions in bacterial pathogenesis

J Poole, CJ Day, M von Itzstein, JC Paton… - Nature Reviews …, 2018 - nature.com
Many important interactions between bacterial pathogens and their hosts are highly specific
binding events that involve host or pathogen carbohydrate structures (glycans). Glycan …

[HTML][HTML] Microbe–host interactions are positively and negatively regulated by galectin–glycan interactions

LG Baum, OB Garner, K Schaefer, B Lee - Frontiers in immunology, 2014 - frontiersin.org
Microbe–host interactions are complex processes that are directly and indirectly regulated
by a variety of factors, including microbe presentation of specific molecular signatures on the …

Glycan: glycan interactions: High affinity biomolecular interactions that can mediate binding of pathogenic bacteria to host cells

CJ Day, EN Tran, EA Semchenko… - Proceedings of the …, 2015 - National Acad Sciences
Cells from all domains of life express glycan structures attached to lipids and proteins on
their surface, called glycoconjugates. Cell-to-cell contact mediated by glycan: glycan …

Sugar coating: bacterial protein glycosylation and host–microbe interactions

FYY Tan, CM Tang, RM Exley - Trends in biochemical sciences, 2015 - cell.com
Bacterial surfaces are rich in glycoconjugates such as capsules, lipopolysaccharides, and
peptidoglycans. The discovery of prokaryotic protein glycosylation systems has revealed that …

Sweet new world: glycoproteins in bacterial pathogens

MA Schmidt, LW Riley, I Benz - TRENDS in Microbiology, 2003 - cell.com
In eukaryotes, the combinatorial potential of carbohydrates is used for the modulation of
protein function. However, despite the wealth of cell wall and surface-associated …

Chemical tools to discover and target bacterial glycoproteins

DH Dube, K Champasa, B Wang - Chemical communications, 2011 - pubs.rsc.org
Bacterial protein glycosylation is an important post-translational modification that can
distinguish pathogenic bacteria from human cells. This review discusses recent findings in …

Sweet talk: protein glycosylation in bacterial interaction with the host

Q Lu, S Li, F Shao - Trends in microbiology, 2015 - cell.com
Pathogenic bacteria encode virulent glycosyltransferases that conjugate various glycans
onto substrate proteins via the N-or O-linkage. The HMW system in nontypeable …

Glycans as legislators of host–microbial interactions: spanning the spectrum from symbiosis to pathogenicity

LV Hooper, JI Gordon - Glycobiology, 2001 - academic.oup.com
The number of microbes associated with our gut likely exceeds our total number of somatic
and germ cells. Despite their numbers, almost nothing is known about the molecular …

Infection, inflammation and host carbohydrates: A Glyco-Evasion Hypothesis

LSC Kreisman, BA Cobb - Glycobiology, 2012 - academic.oup.com
Microbial immune evasion can be achieved through the expression, or mimicry, of host-like
carbohydrates on the microbial cell surface to hide from detection. However, disparate …

Notable aspects of glycan-protein interactions

M Cohen - Biomolecules, 2015 - mdpi.com
This mini review highlights several interesting aspects of glycan-mediated interactions that
are common between cells, bacteria, and viruses. Glycans are ubiquitously found on all …