Autophagy is an essential catabolic process that promotes the clearance of surplus or
damaged intracellular components. Loss of autophagy in age-related human pathologies …

Autophagy is the major intracellular degradation system by which cytoplasmic materials are
delivered to and degraded in the lysosome. However, the purpose of autophagy is not the …

Autophagy is a major cellular metabolic pathway that facilitates degradation of a subset of
long-lived proteins and cytoplasmic organelles in eukaryotic cells. This pathway plays a vital …

Macroautophagy (referred to as autophagy in this review) is a genetically regulated bulk
degradation program conserved from yeast to humans, in which cytoplasmic substrates …

Autophagy is a lysosomal degradation pathway that is essential for survival, differentiation,
development, and homeostasis. Autophagy principally serves an adaptive role to protect …

Autophagy is a highly conserved lysosomal degradation pathway active at basal levels in all
cells. However, under stress conditions, such as a lack of nutrients or trophic factors, it works …

Autophagy degrades the cytoplasmic contents engulfed by autophagosomes. Besides
providing energy and building blocks during starvation via random degradation, autophagy …

Autophagy is a process of cellular self-degradation in which portions of the cytoplasm are
sequestered within cytosolic double-membrane vesicles and delivered to the …

Autophagy is an evolutionarily conserved catabolic process that involves the invagination
and degradation of cytoplasmic components through an autophagosomelysosome track …

Autophagy is a lysosomal degradation pathway of eukaryotic cells that is highly conserved
from yeast to mammals. During this process, cooperating protein complexes are recruited in …