Objectives: To evaluate the ability of body-weight-driven renal function assessment (RFA)
formulae to predict on-target elimination rate ranges for gentamicin in patients with varying …

Objective: To address the background and rationale for the recent introduction of the
Modification of Diet in Renal Disease (MDRD) equation for renal dose adjustment of …

Background: Direct measurement of glomerular filtration rate (GFR) is considered to be the
most accurate method of assessing kidney function, albeit difficult and costly. With the …

Study Objectives. To quantify the difference between glomerular filtration rates (GFRs)
estimated by using the Cockcroft‐Gault and Modification of Diet in Renal Disease (MDRD) …

Study Objectives. To determine the concordance between the Modification of Diet in Renal
Disease (MDRD) and Cockcroft‐Gault equations for glomerular filtration rate (GFR) …

Background Aminoglycoside clearance depends on kidney function, but the A ustralian T
herapeutic G uidelines for antibiotics (version 14, 2010) recommend initial dosing based on …

Background: The Modification of Diet in Renal Disease (MDRD) formula and a modified
version of the Cockcroft-Gault (CGm) formula adjusting for body surface area have been …

Aminoglycosides are an important class of agents that are used in combination antimicrobial
regimens to treat bacterial pathogens. Dosing of aminoglycosides is typically based on total …

Aim To compare gentamicin dose estimates from four predictive methods. Methods A
retrospective study was conducted, comprising patients at Fremantle Hospital who received …

Background It is unclear which renal function equation, employing an isotope dilution mass
spectrometry (IDMS)-aligned creatinine assay, best predicts gentamicin clearance. Methods …