Ultrasound imaging of apoptosis in tumor response: novel preclinical monitoring of photodynamic therapy effects

B Banihashemi, R Vlad, B Debeljevic, A Giles… - Cancer research, 2008 - AACR
High-frequency ultrasound is a novel method to detect apoptotic cell death based on
changes in cell morphology that cause alterations in the viscoelastic and, consequently, the …

Low‐frequency quantitative ultrasound imaging of cell death in vivo

A Sadeghi‐Naini, N Papanicolau, O Falou… - Medical …, 2013 - Wiley Online Library
Purpose: Currently, no clinical imaging modality is used routinely to assess tumor response
to cancer therapies within hours to days of the delivery of treatment. Here, the authors …

Quantitative ultrasound characterization of cancer radiotherapy effects in vitro

RM Vlad, NM Alajez, A Giles, MC Kolios… - International Journal of …, 2008 - Elsevier
PURPOSE: Currently, no routinely used imaging modality is available to assess the tumor
responses to cancer treatment within hours to days after radiotherapy. In this study, we …

High frequency ultrasound tissue characterization and acoustic microscopy of intracellular changes

S Brand, EC Weiss, RM Lemor, MC Kolios - Ultrasound in medicine & …, 2008 - Elsevier
The objective of this work is to investigate changes in the acoustic properties of cells when
exposed to chemotherapy for monitoring treatment response. High frequency ultrasound …

Conventional frequency ultrasonic biomarkers of cancer treatment response in vivo

A Sadeghi-Naini, O Falou, H Tadayyon… - Translational …, 2013 - Elsevier
BACKGROUND: Conventional frequency quantitative ultrasound in conjunction with textural
analysis techniques was investigated to monitor noninvasively the effects of cancer …

Quantitative ultrasound characterization of responses to radiotherapy in cancer mouse models

RM Vlad, S Brand, A Giles, MC Kolios… - Clinical cancer research, 2009 - AACR
Purpose: Currently, no imaging modality is used routinely to assess tumor responses to
radiotherapy within hours to days after the delivery of treatment. In this study, we show the …

Quantitative ultrasound evaluation of tumor cell death response in locally advanced breast cancer patients receiving chemotherapy

A Sadeghi-Naini, N Papanicolau, O Falou… - Clinical Cancer …, 2013 - AACR
Purpose: Quantitative ultrasound techniques have been recently shown to be capable of
detecting cell death through studies conducted on in vitro and in vivo models. This study …

Ultrasound imaging of apoptosis: high-resolution non-invasive monitoring of programmed cell death in vitro, in situ and in vivo

GJ Czarnota, MC Kolios, J Abraham, M Portnoy… - British journal of …, 1999 - nature.com
A new non-invasive method for monitoring apoptosis has been developed using high
frequency (40 MHz) ultrasound imaging. Conventional ultrasound backscatter imaging …

[HTML][HTML] Quantification of ultrasonic scattering properties of in vivo tumor cell death in mouse models of breast cancer

H Tadayyon, L Sannachi, A Sadeghi-Naini… - Translational …, 2015 - Elsevier
INTRODUCTION: Quantitative ultrasound parameters based on form factor models were
investigated as potential biomarkers of cell death in breast tumor (MDA-231) xenografts …

Bioeffects of low‐intensity ultrasound in vitro: apoptosis, protein profile alteration, and potential molecular mechanism

Y Feng, Z Tian, M Wan - Journal of ultrasound in medicine, 2010 - Wiley Online Library
Objective. The purpose of this study was to evaluate the potential molecular mechanism of
low‐intensity ultrasound‐induced apoptosis by analyzing protein profile alteration in …