Highly selective and non-radioactive Raman detection of the biochemical composition of
living single-cell is a key method of evaluating complex biological reaction processes …

Surface plasmon-coupled emission has been widely used in fluorescence imaging,
biochemical sensing, and enhanced Raman spectroscopy. A self-referenced directional …

A novel tubular waveguide particle plasmon resonance (TW-PPR) sensor is demonstrated
for label-free biochemical detection. The sensor itself is a microchamber of a defined sample …

Raman scattering can provide information on molecular fingerprints, which have been
widely applied in various fields of material science and nanobiotechnology. Notably, low …

Raman microspectroscopy is one of the most powerful tools in molecular sensing, offering a
non-invasive and comprehensive characterization of the intracellular environment. To …

Single-cell analysis provides an important strategy to evaluate cellular heterogeneity.
Although surface-enhanced Raman scattering (SERS) has been considered as a promising …

Biomarkers detection at an ultra-low concentration in biofluids (blood, serum, saliva, etc.) is
a key point for the early diagnosis success and the development of personalized therapies …

Our current understanding of molecular biology provides a clear picture of how the genome,
transcriptome and proteome regulate each other, but how the chemical environment of the …

The analysis of in situ single cells in tissue is crucial for the study of tumors. However,
simultaneous analysis of multiple biomolecules for single cells by fluorescence …

Surface-enhanced Raman spectroscopy (SERS) is a highly efficient optical technique that
employs metallic nanostructures to amplify the inherently weak Raman signals. Despite its …