Human papillomavirus 11 early protein E6 activates autophagy by repressing AKT/mTOR and Erk/mTOR

B Zhang, Y Song, S Sun, R Han, C Hua… - Journal of …, 2019 - Am Soc Microbiol
Low-risk human papillomaviruses (LR-HPVs) are the causative agents of genital warts,
which are a widespread sexually transmitted disease. How LR-HPVs affect autophagy and …

[HTML][HTML] Expression of the human papillomavirus type 16 E7 oncoprotein induces an autophagy-related process and sensitizes normal human keratinocytes to cell …

X Zhou, K Münger - Virology, 2009 - Elsevier
Expression of oncogenes, such as the human papillomavirus type 16 (HPV16) E7
oncoprotein, promotes aberrant cell proliferation. In the absence of concurrent mitogenic …

Human papillomavirus type 16 early protein E7 activates autophagy through inhibition of dual‐specificity phosphatase 5

C Hua, Q Zheng, J Zhu, S Chen, Y Song… - Oxidative Medicine …, 2022 - Wiley Online Library
Consistent high‐risk human papillomavirus (HPV) infection leads to various malignant
cancers. Autophagy can promote cancer progression by helping cancer cells survive under …

Cellular entry of human papillomavirus type 16 involves activation of the phosphatidylinositol 3-kinase/Akt/mTOR pathway and inhibition of autophagy

Z Surviladze, RT Sterk, SA DeHaro… - Journal of virology, 2013 - Am Soc Microbiol
The mammalian target of rapamycin (mTOR) downstream of phosphatidylinositol 3-kinase
(PI3K) in the growth factor receptor (GFR) pathway is a crucial metabolic sensor that …

[HTML][HTML] HPV16 E5 deregulates the autophagic process in human keratinocytes

F Belleudi, M Nanni, S Raffa, MR Torrisi - Oncotarget, 2015 - ncbi.nlm.nih.gov
Autophagy plays key roles during host defense against pathogens, but viruses have evolved
strategies to block the process or to exploit it for replication and successful infection. The E5 …

[HTML][HTML] Autophagy is induced in human keratinocytes during human papillomavirus 11 pseudovirion entry

R Han, C Hua, S Sun, B Zhang, Y Song… - Aging (Albany …, 2020 - ncbi.nlm.nih.gov
Abstract Human papillomavirus type 11 (HPV11) is one of the main causes of condyloma
acuminatum, a widespread sexually transmitted disease. During infection of its primary …

Regulation of autophagy by high‐and low‐risk human papillomaviruses

AK Aranda‐Rivera, A Cruz‐Gregorio… - Reviews in Medical …, 2021 - Wiley Online Library
While high‐risk human papillomavirus (HR‐HPV) infection is related to the development of
cervical, vulvar, anal, penile and oropharyngeal cancer, low‐risk human papillomavirus (LR …

Human papillomavirus 16E6/E7 activates autophagy via Atg9B and LAMP1 in cervical cancer cells

C Tingting, Y Shizhou, Z Songfa, X Junfen… - Cancer …, 2019 - Wiley Online Library
Backgrounds Although the role of high‐risk human papillomavirus (HPV) E6 and E7 in
cellular malignant transformation has been elucidated, the function of both genes in cellular …

HPV E6 promotes cell proliferation of cervical cancer cell by accelerating accumulation of RBM15 dependently of autophagy inhibition

G Nie, B Tang, M Lv, D Li, T Li, R Ou… - Cell Biology …, 2023 - Wiley Online Library
The mechanism of m6A modification in HPV‐related cervical cancer remains unclear. This
study explored the role of methyltransferase components in HPV‐related cervical cancer …

The autophagy process in cervical carcinogenesis: Role of non-Coding-RNAs, molecular mechanisms, and therapeutic targets

A Lagunas-Martínez, V Madrid-Marina… - Cells, 2022 - mdpi.com
Autophagy is a highly conserved multistep lysosomal degradation process in which cellular
components are localized to autophagosomes, which subsequently fuse with lysosomes to …