Background Elevated evidence suggests that the SENPs family plays an important role in
tumor progression. However, the role of SENPs in AML remains unclear. Methods We …

Sentrin specific-protease 1 (SENP1) is a protein involved in deSUMOylation that is almost
overexpressed in cancer. SENP1 has a determinative role in the activation of transcription …

Objectives: Long non-coding RNA (lncRNA) small nucleolar RNA host gene 4 (SNHG4) is a
characterized oncogenic lncRNA in osteosarcoma. The analysis of the TCGA dataset …

Chronic lymphocytic leukemia (CLL) is one of the most often diagnosed hematological
malignant tumors in the Western world and a type of inert B-cell lymphoma that commonly …

To investigate the roles of SUMO-specific protease 1 (SENP1) in triple-negative breast
cancer (TNBC), we detected the expression level of SENP1 in the clinical samples of TNBC …

Purpose Esophageal squamous cell carcinoma (ESCC) is a prevalent tumor in the
gastrointestinal tract, but our understanding of the molecular mechanisms underlying ESCC …

TNBC is characterized by high incidence of visceral metastasis and lacks effective clinical
targets. This study aims to delineate the molecular mechanisms of SENP1 in TNBC invasion …

Small ubiquitin-like modifier (SUMO)/sentrin‑specific protease 1 (SENP1), a member of the
SENP family, is highly expressed in several neoplastic tissues. However, the effect of …

Objectives: This study aimed to investigate the effect of specific small ubiquitin-like modifier
(SUMO) proteases 1 (SENP1)-mediated deSUMOylation on the malignant behavior of …

Acute myeloid leukemia (AML) is the second most common hematological malignancy after
lymphoma in the world. Long non-coding RNAs (LncRNAs) have been suggested as key …