El cardiomiocito, la célula contráctil del corazón, requiere el suministro continuo de energía
para llevar a cabo la contracción muscular y sus diversos procesos celulares que incluyen …

La testosterona es la principal hormona sexual masculina, responsable de múltiples efectos
en el organismo. Dentro de estos, se ha descrito que es capaz de producir hipertrofia …

Skeletal and cardiac muscle depend on high turnover of ATP made by mitochondria in order
to contract efficiently. The transcriptional coactivator PGC-1α has been shown to function as …

Background Testosterone regulates nutrient and energy balance to maintain protein
synthesis and metabolism in cardiomyocytes, but supraphysiological concentrations induce …

Background Testosterone regulates nutrient and energy balance to maintain protein
synthesis and metabolism in cardiomyocytes, but supraphysiological concentrations induce …

Testosterone exerts important effects in the heart. Cardiomyocytes are target cells for
androgens, and testosterone induces rapid effects via Ca2+ release and protein kinase …

The beating heart consumes more ATP per weight than any other organ. The machineries
required for this are many and complex. Fuel and oxygen must be transported via the …

The anabolic hormone testosterone is associated with cardiac hypertrophy, but the signal
transduction mechanisms involved are poorly known. In this work, primary cultures of …

The present study investigated whether exercise induces the expression of PGC-1α splice
variants in human skeletal muscle and the possible influence of metabolic perturbation on …

Male mice with elimination of the androgen receptor (AR) in islet β cells (βARKO) exhibit
blunted glucose-stimulated insulin secretion (GSIS), leading to hypoinsulinemia and …