Ancient metagenomic studies: considerations for the wider scientific community
Like modern metagenomics, ancient metagenomics is a highly data-rich discipline, with the
added challenge that the DNA of interest is degraded and, depending on the sample type, in …
added challenge that the DNA of interest is degraded and, depending on the sample type, in …
Community-curated and standardised metadata of published ancient metagenomic samples with AncientMetagenomeDir
Ancient DNA and RNA are valuable data sources for a wide range of disciplines. Within the
field of ancient metagenomics, the number of published genetic datasets has risen …
field of ancient metagenomics, the number of published genetic datasets has risen …
metaDMG–a fast and accurate ancient DNA damage toolkit for metagenomic data
C Michelsen, MW Pedersen, A Fernandez-Guerra… - bioRxiv, 2022 - biorxiv.org
Motivation Under favourable conditions DNA molecules can persist for hundreds of
thousands of years. Such genetic remains make up invaluable resources to study past …
thousands of years. Such genetic remains make up invaluable resources to study past …
aMeta: an accurate and memory-efficient ancient metagenomic profiling workflow
Abstract Analysis of microbial data from archaeological samples is a growing field with great
potential for understanding ancient environments, lifestyles, and diseases. However, high …
potential for understanding ancient environments, lifestyles, and diseases. However, high …
The metagenomic data life-cycle: standards and best practices
Metagenomics data analyses from independent studies can only be compared if the
analysis workflows are described in a harmonized way. In this overview, we have mapped …
analysis workflows are described in a harmonized way. In this overview, we have mapped …
Proper authentication of ancient DNA is still essential
R Eisenhofer, LS Weyrich - Genes, 2018 - mdpi.com
Santiago-Rodriguez et al.[1] report on the putative gut microbiome and resistome of Inca and
Italian mummies, and find that Italian mummies exhibit higher bacterial diversity compared to …
Italian mummies, and find that Italian mummies exhibit higher bacterial diversity compared to …
Characterization of ancient and modern genomes by SNP detection and phylogenomic and metagenomic analysis using PALEOMIX
M Schubert, L Ermini, CD Sarkissian, H Jónsson… - Nature protocols, 2014 - nature.com
Next-generation sequencing technologies have revolutionized the field of paleogenomics,
allowing the reconstruction of complete ancient genomes and their comparison with modern …
allowing the reconstruction of complete ancient genomes and their comparison with modern …
Comparative analysis of functional metagenomic annotation and the mappability of short reads
R Carr, E Borenstein - PloS one, 2014 - journals.plos.org
To assess the functional capacities of microbial communities, including those inhabiting the
human body, shotgun metagenomic reads are often aligned to a database of known genes …
human body, shotgun metagenomic reads are often aligned to a database of known genes …
Benchmarking Metagenomic Classifiers on Simulated Ancient and Modern Metagenomic Data
V Pusadkar, RK Azad - Microorganisms, 2023 - mdpi.com
Taxonomic profiling of ancient metagenomic samples is challenging due to the
accumulation of specific damage patterns on DNA over time. Although a number of methods …
accumulation of specific damage patterns on DNA over time. Although a number of methods …
[PDF][PDF] Metagenomics and beyond: current approaches and integration with complementary technologies
TL Meiring, R Bauer, I Scheepers… - … and future trends, 2011 - researchgate.net
Metagenomics is the cultivation independent analysis of the collective genomes of microbes
within a given environment, using sequence-and functionbased approaches. Early …
within a given environment, using sequence-and functionbased approaches. Early …