Efficacy and safety of oral Nigella sativa oil for symptomatic treatment of knee osteoarthritis: A double-blind, randomized, placebo-controlled clinical trial

HF Huseini, R Mohtashami, E Sadeghzadeh… - … Therapies in Clinical …, 2022 - Elsevier
Background and purpose The oil of Nigella sativa (NS) seeds has analgesic and anti-
inflammatory effects. Therefore, the efficacy and safety of NS oil in the treatment of knee …

The effects of topical and oral Nigella sativa oil on clinical findings in knee osteoarthritis: A double-blind, randomized controlled trial

N Dolatkhah, AA Afshar, S Sharifi, M Rahbar… - Journal of Herbal …, 2022 - Elsevier
Introduction The objective of this trial was to determine the efficacy and safety of topical and
oral application of Nigella sativa (N. Sativa) oil compared to the placebo in knee …

The efficacy and safety of Nigella sativa in the management of osteoarthritis: A systematic review

SE Mousavi, M Noori, H Marandi… - Health Science …, 2024 - Wiley Online Library
Abstract Background and Aims Osteoarthritis (OA) is one of the most common debilitating
diseases among the aging population. Nigella sativa is one potential treatment for OA. Here …

[HTML][HTML] Effect of topical application of Nigella sativa oil and oral acetaminophen on pain in elderly with knee osteoarthritis: a crossover clinical trial

A Kooshki, R Forouzan, MH Rakhshani… - Electronic …, 2016 - ncbi.nlm.nih.gov
Background Limited evidence supports Nigella sativa's role as an effective complementary
and alternative medicine and the anti-inflammatory effects of Nigella sativa on patients with …

Nigella sativa fixed oil as alternative treatment in management of pain in arthritis rheumatoid

M Mahboubi, LMT Kashani, M Mahboubi - Phytomedicine, 2018 - Elsevier
Background N. sativa seeds is the source of fixed oil, which contain fatty acids and
thymoquinone. N. sativa fixed oil topically or orally is used traditionally for management of …

Effectiveness of Nigella sativa Oil in the Management of Rheumatoid Arthritis Patients: A Placebo Controlled Study

TA Gheita, SA Kenawy - Phytotherapy research, 2012 - Wiley Online Library
The constituents of Nigella sativa modulate the immune system. The aim of the present work
was to study the effectiveness of Nigella sativa oil in RA patients. Data from 40 female RA …

Comparison of the effect of topical use of Nigella Sativa oil and diclofenac gel on osteoarthritis pain in older people: A randomized, double-blind, clinical trial

F Azizi, F Ghorat, MH Rakhshani, M Rad - Journal of Herbal Medicine, 2019 - Elsevier
Osteoarthritis is one of the most common diseases in the elderly. Herbal remedies create
pain relief with appropriate clinical effects and less toxicity. We aimed to investigate the …

[HTML][HTML] Chondroprotective effect of Nigella sativa oil in the early stages of osteoarthritis: An experimental study in rabbits

Y Turhan, M Arıcan, ZO Karaduman… - … of Musculoskeletal & …, 2019 - ncbi.nlm.nih.gov
Purpose: Nigella sativa oil possesses a well-known ability to protect certain organs from
oxidative, neoplastic, and inflammatory damage. This study investigated the potential …

[HTML][HTML] Effects of Nigella sativa oil extract on inflammatory cytokine response and oxidative stress status in patients with rheumatoid arthritis: a randomized, double …

V Hadi, S Kheirouri, M Alizadeh… - Avicenna journal of …, 2016 - ncbi.nlm.nih.gov
Objective: Nigella sativa is a medicinal plant that has long been used in traditional medicine
for treating various conditions. Numerous animal studies provided evidences that the seed …

Effect of an orally formulated processed black cumin, from Iranian traditional medicine pharmacopoeia, in relieving symptoms of knee osteoarthritis: a prospective …

A Salimzadeh, A Ghourchian… - International Journal …, 2017 - Wiley Online Library
Aim Osteoarthritis is a global health problem, especially for the elderly. A good replacement
for non‐surgical treatments is the use of traditional medicines. We selected a revere plant …