Refined prognostic evaluation in colon carcinoma using immunohistochemical galectin fingerprinting

N Nagy, H Legendre, O Engels, S André… - … Journal of the …, 2003 - Wiley Online Library
BACKGROUND Knowledge of the expression of the galectins in human colon carcinomas is
mainly restricted to galectin‐3 and, to a lesser extent, galectin‐1. The current study analyzed …

Galectin-3 expression is a potent prognostic marker in colorectal cancer

K Endo, S Kohnoe, E Tsujita, A Watanabe… - Anticancer …, 2005 - ar.iiarjournals.org
Background: Galectin-3 is a β-galactoside-binding protein whose expression has been
correlated with progression and metastasis in colon cancer. It is expressed at elevated …

The growing galectin network in colon cancer and clinical relevance of cytoplasmic galectin-3 reactivity

H Dawson, S Andre, E Karamitopoulou… - Anticancer …, 2013 - ar.iiarjournals.org
Background/Aim: Human lectins translate sugar-encoded signals of cell surface
glycoconjugates into biological effects, and this is what is known for the adhesion/growth …

Immunoexpression of galectin-3 in colorectal cancer and its relationship with survival

L Zaia Povegliano, CTF Oshima… - Journal of …, 2011 - Springer
Introduction Galectin-3 is an endogenous galactose-binding protein that is expressed in a
wide range of normal and neoplasic tissues and is thought to be involved in cellular …

Clinical significance of circulating galectins as colorectal cancer markers

M Watanabe, I Takemasa, N Kaneko… - Oncology …, 2011 - spandidos-publications.com
The utility of CEA and CA19-9 as colorectal carcinoma (CRC) markers is limited and
development of additional reliable markers is under investigation. We previously showed …

Expression of an endogenous galactose‐binding lectin correlates with neoplastic progression in the colon

HL Schoeppner, A Raz, SB Ho, RS Bresalier - Cancer, 1995 - Wiley Online Library
Background. Galectin‐3 is an endogenous galactose‐binding protein that is expressed in a
wide range of normal and neoplastic tissues and is thought to be involved in cellular …

Increased expression of galectin-3 in primary gastric cancer and the metastatic lymph nodes

J Miyazaki, R Hokari, S Kato, Y Tsuzuki… - Oncology …, 2002 - spandidos-publications.com
Abstract Galectin-3, a multifunctional β-galactocide binding lectin possibly participates in a
variety of biological events including cell proliferation, differentiation, and apoptosis. The …

Differential expression of galectin 3 and galectin 1 in colorectal cancer progression

X Sanjuan, PL Fernandez, A Castells, V Castronovo… - Gastroenterology, 1997 - Elsevier
BACKGROUND & AIMS: Galectins are beta-galactoside-binding proteins possibly involved
in tumor progression. The aim of this study was to determine the pattern of galectin 3 and …

Galectin-3 may serve as a marker for poor prognosis in colorectal cancer: A meta-analysis

C Wang, X Zhou, L Ma, Y Zhuang, Y Wei… - … -Research and Practice, 2019 - Elsevier
Galectin-3 has an important function in the development of tumors. The purpose of this meta-
analysis was to explore the relationships between the expression of galectin-3 on …

Galectin-8 expression decreases in cancer compared with normal and dysplastic human colon tissue and acts significantly on human colon cancer cell migration as a …

N Nagy, Y Bronckart, I Camby, H Legendre, H Lahm… - Gut, 2002 - gut.bmj.com
Background and aims: Galectins are β-galactoside binding proteins. This ability may have a
bearing on cell adhesion and migration/proliferation in human colon cancer cells. In addition …