Translational studies have significantly advanced our understanding of the molecular
pathogenesis of adrenal cortical neoplasia in the past decade [1]. Recognition of the high …

The new WHO classification of adrenal cortical proliferations reflects translational advances
in the fields of endocrine pathology, oncology and molecular biology. By adopting a …

Non-neoplastic lesions were added in the 5th edition WHO classification of adrenal cortical
tumor based on the recent update, including adrenal rests, adrenal cysts, congenital adrenal …

Adrenal neoplasms present unique diagnostic and management challenges in pediatric
patients related to both their rare and often highly aggressive nature. Although significant …

Context: Childhood adrenocortical tumors (ACT) are rare malignancies, except in southern
Brazil, where a higher incidence rate is associated to a high frequency of the founder R337H …

Approximately one-tenth of the general population exhibit adrenal cortical nodules, and the
incidence has increased. Afflicted patients display a multifaceted symptomatology …

Adrenocortical carcinomas are rare tumours that can be diagnostically challenging.
Numerous multiparametric scoring systems and diagnostic algorithms have been proposed …

Pediatric adrenal tumors are unique entities with specific diagnostic, prognostic, and
therapeutic challenges. The adrenal medulla gives rise to peripheral neuroblastic tumors …

Adrenal tumors are quite rare in infancy and childhood with the exception of neuroblastoma.
In fact, adrenocortical tumors (ACT) account for only 0.2% of all malignant cancers in …

The prognosis of malignant pediatric adrenocortical tumors is closely related to disease
stage, which is used to guide perioperative treatment recommendations. However, current …