Cytotoxicity and mechanism of action of metal complexes: An overview

S Abdolmaleki, S Khaksar, A Aliabadi, A Panjehpour… - Toxicology, 2023 - Elsevier
After the discovery of cisplatin, many metal compounds were investigated for the therapy of
diseases, especially cancer. The high therapeutic potential of metal-based compounds is …

The role of metals in the next generation of anticancer therapeutics

JJ Wilson, TC Johnstone - Current Opinion in Chemical Biology, 2023 - Elsevier
Conclusion We very much appreciated working with all the authors noted above on
assembling this special issue and we hope that you enjoy reading their excellent …

A survey of the mechanisms of action of anticancer transition metal complexes

M Marloye, G Berger, M Gelbcke… - Future medicinal …, 2016 - Taylor & Francis
Metal complexes have been the subject of numerous investigations in oncology but, despite
the plethora of newly synthesized compounds, their precise mechanisms of action remain …

Metal anticancer complexes–activity, mechanism of action, future perspectives

E Alessio, Z Guo - European journal of inorganic chemistry, 2017 - Wiley Online Library
Guest editors Enzo Alessio and Zijian Guo present an overview of the topics reported in the
papers of this issue, listing the general trends that dominate the field of metal anticancer …

Metallomics insights into the programmed cell death induced by metal-based anticancer compounds

CP Tan, YY Lu, LN Ji, ZW Mao - Metallomics, 2014 - academic.oup.com
Since the discovery of cisplatin more than 40 years ago, enormous research efforts have
been dedicated to developing metal-based anticancer agents and to elucidating the …

Copper complexes as anticancer agents

C Marzano, M Pellei, F Tisato… - Anti-Cancer Agents in …, 2009 - ingentaconnect.com
Metal-based antitumor drugs play a relevant role in antiblastic chemotherapy. Cisplatin is
regarded as one of the most effective drugs, even if severe toxicities and drug resistance …

Metal Complexes in cancer treatment: Journey so far

A Kumar Singh, A Kumar, H Singh… - Chemistry & …, 2023 - Wiley Online Library
Metal complexes in cancer therapy have attracted much interest mainly because metals
exhibit unique characteristics, such as redox activity, metal‐ligand interaction, structure and …

Recent advances and future development of metal complexes as anticancer agents

P Jia, R Ouyang, P Cao, X Tong, X Zhou… - Journal of …, 2017 - Taylor & Francis
Since the initial discovery of applications of platinum complexes in the clinical treatment of
many kinds of cancers, the efficiency of platinum complexes in inhibiting the proliferation of …

Recent researches in metal supramolecular complexes as anticancer agents

CH Zhou, YY Zhang, CY Yan, K Wan… - Anti-Cancer Agents in …, 2010 - ingentaconnect.com
The research and development of metal supramolecular complexes as anticancer
supramolecular drugs, which are aggregates mainly formed by one or more inorganic metal …

Riding the metal wave: A review of the latest developments in metal-based anticancer agents

S Abdolmaleki, A Aliabadi, S Khaksar - Coordination Chemistry Reviews, 2024 - Elsevier
Metal-based complexes have demonstrated significant anticancer effects and have emerged
as candidates with great potential for cancer therapy. These agents are effective in a variety …