Metabolomics in systems biology
W Weckwerth - Annual review of plant biology, 2003 - annualreviews.org
The primary aim of “omic” technologies is the nontargeted identification of all gene products
(transcripts, proteins, and metabolites) present in a specific biological sample. By their …
(transcripts, proteins, and metabolites) present in a specific biological sample. By their …
Plant metabolomics and its potential for systems biology research: Background concepts, technology, and methodology
The “metabolome” comprises the entire complement of small molecules in a plant or any
other organism. It represents the ultimate phenotype of cells, deduced from the perturbation …
other organism. It represents the ultimate phenotype of cells, deduced from the perturbation …
Integrated omics approaches in plant systems biology
Understanding cellular metabolic systems is vital not only for determining the function of
enzymatic genes, but also for elucidating the coordination among various metabolic …
enzymatic genes, but also for elucidating the coordination among various metabolic …
Integration of metabolomics data into metabolic networks
N Töpfer, S Kleessen, Z Nikoloski - Frontiers in plant science, 2015 - frontiersin.org
Metabolite levels together with their corresponding metabolic fluxes are integrative
outcomes of biochemical transformations and regulatory processes and they can be used to …
outcomes of biochemical transformations and regulatory processes and they can be used to …
Plant metabolomics: current initiatives and future prospects
S Manickam, VR Rajagopalan, R Kambale… - Current Issues in …, 2023 - mdpi.com
Plant metabolomics is a rapidly advancing field of plant sciences and systems biology. It
involves comprehensive analyses of small molecules (metabolites) in plant tissues and …
involves comprehensive analyses of small molecules (metabolites) in plant tissues and …
Can we discover novel pathways using metabolomic analysis?
W Weckwerth, O Fiehn - Current opinion in biotechnology, 2002 - Elsevier
Metabolomic analysis aims at the identification and quantitation of all metabolites in a given
biological sample. Current data acquisition and network analysis strategies are classified on …
biological sample. Current data acquisition and network analysis strategies are classified on …
Metabolomics for functional genomics, systems biology, and biotechnology
Metabolomics now plays a significant role in fundamental plant biology and applied
biotechnology. Plants collectively produce a huge array of chemicals, far more than are …
biotechnology. Plants collectively produce a huge array of chemicals, far more than are …
Recent progress in the development of metabolome databases for plant systems biology
A Fukushima, M Kusano - Frontiers in plant science, 2013 - frontiersin.org
Metabolomics has grown greatly as a functional genomics tool, and has become an
invaluable diagnostic tool for biochemical phenotyping of biological systems. Over the past …
invaluable diagnostic tool for biochemical phenotyping of biological systems. Over the past …
Plant metabolomics: towards biological function and mechanism
N Schauer, AR Fernie - Trends in plant science, 2006 - cell.com
Metabolite profiling is a fast growing technology and is useful for phenotyping and
diagnostic analyses of plants. It is also rapidly becoming a key tool in functional annotation …
diagnostic analyses of plants. It is also rapidly becoming a key tool in functional annotation …
Metabolomics: an integral technique in systems biology
W Weckwerth - Bioanalysis, 2010 - Taylor & Francis
Metabolomics is the unbiased identification and state-specific quantification of all
metabolites in a cell, tissue or whole organism, and has developed rapidly into one of the …
metabolites in a cell, tissue or whole organism, and has developed rapidly into one of the …