Metformin is a first-line drug for treating type 2 diabetes mellitus (T2DM) and one of the most
commonly prescribed drugs in the world. Besides its hypoglycemic effects, metformin also …

Metformin as a first-line drug for type 2 diabetes mellitus (T2DM) treatment is widely studied.
Metformin can reduce liver glucose output and improve insulin resistance. Recent evidence …

Metformin, one of the first-line of hypoglycemic drugs, has cardioprotective, anti-
inflammatory and anticancer activities, in addition to its proven hypoglycemic effects …

Metabolic stress, transduced as an altered cellular redox and energy status, presents as the
main culprit in many diseases, including diabetes. However, its role in the pathology of …

Metformin is a drug in the family of biguanide compounds that is widely used in the treatment
of type 2 diabetes (T2D). Interestingly, the therapeutic potential of metformin expands its …

Alzheimer's disease (AD) is the most common neurodegenerative disease, which results in
dementia typically in the elderly. The disease is mainly characterized by the deposition of …

Parkinson's disease (PD) is a common neurodegenerative disease developed due to the
degeneration of dopaminergic neurons in the substantia nigra. There is no single effective …

Diabetes mellitus (DM) is a metabolic disease that activates several molecular pathways
involved in neurodegenerative disorders. Metformin, an anti-hyperglycemic drug used for …

The search for treatments for neurodegenerative diseases is a major concern in light of
today's aging population and an increasing burden on individuals, families, and society …

Metformin is currently the most effective treatment for type-2 diabetes. The beneficial actions
of metformin have been found even beyond diabetes management and it has been …