Iron metabolism: pathophysiology and pharmacology
K Roemhild, F von Maltzahn, R Weiskirchen… - Trends in …, 2021 - cell.com
Iron is essential in many physiological processes, including DNA metabolism, oxygen
transport, and cellular energy generation. Deregulated iron metabolism, which results in iron …
transport, and cellular energy generation. Deregulated iron metabolism, which results in iron …
Targeting iron metabolism in drug discovery and delivery
BJ Crielaard, T Lammers, S Rivella - Nature Reviews Drug Discovery, 2017 - nature.com
Iron fulfils a central role in many essential biochemical processes in human physiology; thus,
proper processing of iron is crucial. Although iron metabolism is subject to relatively strict …
proper processing of iron is crucial. Although iron metabolism is subject to relatively strict …
Role of iron in the molecular pathogenesis of diseases and therapeutic opportunities
U Abbasi, S Abbina, A Gill, LE Takuechi… - ACS Chemical …, 2021 - ACS Publications
Iron is an essential mineral that serves as a prosthetic group for a variety of proteins involved
in vital cellular processes. The iron economy within humans is highly conserved in that there …
in vital cellular processes. The iron economy within humans is highly conserved in that there …
Iron metabolism and toxicity
G Papanikolaou, K Pantopoulos - Toxicology and applied pharmacology, 2005 - Elsevier
Iron is an essential nutrient with limited bioavailability. When present in excess, iron poses a
threat to cells and tissues, and therefore iron homeostasis has to be tightly controlled. Iron's …
threat to cells and tissues, and therefore iron homeostasis has to be tightly controlled. Iron's …
[HTML][HTML] The role of iron regulation in immunometabolism and immune-related disease
Immunometabolism explores how the intracellular metabolic pathways in immune cells can
regulate their function under different micro-environmental and (patho-)-physiological …
regulate their function under different micro-environmental and (patho-)-physiological …
[HTML][HTML] Balancing acts: molecular control of mammalian iron metabolism
Iron is ubiquitous in the environment and in biology. The study of iron biology focuses on
physiology and homeostasis—understanding how cells and organisms regulate their iron …
physiology and homeostasis—understanding how cells and organisms regulate their iron …
[HTML][HTML] Altered iron metabolism and impact in cancer biology, metastasis, and immunology
Iron is an essential nutrient that plays a complex role in cancer biology. Iron metabolism
must be tightly controlled within cells. Whilst fundamental to many cellular processes and …
must be tightly controlled within cells. Whilst fundamental to many cellular processes and …
[图书][B] Iron metabolism: from molecular mechanisms to clinical consequences
R Crichton - 2016 - books.google.com
Iron is indispensable for the growth, development and well-being of almost all living
organisms. Biological systems from bacteria, fungi and plants to humans have evolved …
organisms. Biological systems from bacteria, fungi and plants to humans have evolved …
Iron is hot: an update on the pathophysiology of hemochromatosis
NC Andrews, JE Levy - Blood, The Journal of the American …, 1998 - ashpublications.org
GENETIC IRON OVERLOAD disorders are prevalent yet poorly understood. Over the past 3
years, the discoveries of the hereditary hemochromatosis gene and an intestinal iron …
years, the discoveries of the hereditary hemochromatosis gene and an intestinal iron …
New insights into iron regulation and erythropoiesis
A Kim, E Nemeth - Current opinion in hematology, 2015 - journals.lww.com
New insights into iron regulation and erythropoiesis : Current Opinion in Hematology New
insights into iron regulation and erythropoiesis : Current Opinion in Hematology Log in or …
insights into iron regulation and erythropoiesis : Current Opinion in Hematology Log in or …