[HTML][HTML] Marker expression reveals heterogeneity of spermatogonia in the neonatal mouse testis

BA Niedenberger, JT Busada… - Reproduction (Cambridge …, 2015 - ncbi.nlm.nih.gov
Prospermatogonia transition into type A spermatogonia, which provide the source for the
spermatogonial stem cell (SSC) pool. A percentage of these type A spermatogonia then …

Transcriptional and translational heterogeneity among neonatal mouse spermatogonia

BP Hermann, KN Mutoji, EK Velte, D Ko… - Biology of …, 2015 - academic.oup.com
Spermatogonial stem cells (SSCs) are a subset of undifferentiated spermatogonia
responsible for ongoing spermatogenesis in mammalian testes. Spermatogonial stem cells …

Differential RA responsiveness directs formation of functionally distinct spermatogonial populations at the initiation of spermatogenesis in the mouse

EK Velte, BA Niedenberger, ND Serra, A Singh… - …, 2019 - journals.biologists.com
In the mammalian testis, sustained spermatogenesis relies on spermatogonial stem cells
(SSCs); their progeny either remain as stem cells (self-renewal) or proliferate and …

Distribution of GFRA1-expressing spermatogonia in adult mouse testis

M Grasso, A Fuso, L Dovere, DG de Rooij… - …, 2012 - rep.bioscientifica.com
In mice and other mammals, spermatogenesis is maintained by spermatogonial stem cells
(SSCs), a cell population belonging to undifferentiated type A spermatogonia. In the …

Function and transcriptomic dynamics of Sertoli cells during prospermatogonia development in mouse testis

RG Yan, BY Li, QE Yang - Reproductive Biology, 2020 - Elsevier
In mammals, spermatogonial stem cells (SSCs) arise from a subpopulation of
prospermatogonia during neonatal testis development. Currently, molecular mechanisms …

The molecular signature of spermatogonial stem/progenitor cells in the 6-day-old mouse testis

M Kokkinaki, TL Lee, Z He, J Jiang… - Biology of …, 2009 - academic.oup.com
To characterize the molecular phenotype of spermatogonial stem cells (SSCs), we
examined genes that are differentially expressed in the stem/progenitor spermatogonia …

Setting the stage: the first round of spermatogenesis

CB Geyer - The Biology of mammalian spermatogonia, 2017 - Springer
The first round, or wave, of spermatogenesis is the postnatal process of male
gametogenesis that begins with the differentiation of the first subset of spermatogonia and …

Proper timing of a quiescence period in precursor prospermatogonia is required for stem cell pool establishment in the male germline

G Du, MJ Oatley, NC Law, C Robbins, X Wu… - …, 2021 - journals.biologists.com
The stem cell-containing undifferentiated spermatogonial population in mammals, which
ensures continual sperm production, arises during development from prospermatogonial …

[HTML][HTML] Gonocytes-to-spermatogonia transition initiates prior to birth in murine testes and it requires FGF signaling

HP Pui, Y Saga - Mechanisms of development, 2017 - Elsevier
Spermatogenesis is a continuous and highly coordinated process of spermatozoa
production. In mice, this process is believed to initiate shortly after birth with the emergence …

Spermatogonial kinetics in humans

S Di Persio, R Saracino, S Fera, B Muciaccia… - …, 2017 - journals.biologists.com
The human spermatogonial compartment is essential for daily production of millions of
sperm. Despite this crucial role, the molecular signature, kinetic behavior and regulation of …