From AKI to CKD: maladaptive repair and the underlying mechanisms

Z Wang, C Zhang - International journal of molecular sciences, 2022 - mdpi.com
Acute kidney injury (AKI) is defined as a pathological condition in which the glomerular
filtration rate decreases rapidly over a short period of time, resulting in changes in the …

Molecular mechanisms of kidney injury and repair

S Rayego-Mateos, L Marquez-Expósito… - International journal of …, 2022 - mdpi.com
Chronic kidney disease (CKD) will become the fifth global cause of death by 2040, thus
emphasizing the need to better understand the molecular mechanisms of damage and …

[HTML][HTML] AKI on CKD: heightened injury, suppressed repair, and the underlying mechanisms

L He, Q Wei, J Liu, M Yi, Y Liu, H Liu, L Sun, Y Peng… - Kidney international, 2017 - Elsevier
Acute kidney injury (AKI) and chronic kidney disease (CKD) are interconnected. Although
AKI-to-CKD transition has been intensively studied, the information of AKI on CKD is very …

Molecular mechanisms of the acute kidney injury to chronic kidney disease transition: an updated view

F Guzzi, L Cirillo, RM Roperto, P Romagnani… - International journal of …, 2019 - mdpi.com
Increasing evidence has demonstrated the bidirectional link between acute kidney injury
(AKI) and chronic kidney disease (CKD) such that, in the clinical setting, the new concept of …

Recent advances in acute kidney injury and its consequences and impact on chronic kidney disease

A Zuk, JV Bonventre - Current opinion in nephrology and …, 2019 - journals.lww.com
Recent advances in acute kidney injury and its consequences... : Current Opinion in
Nephrology and Hypertension Recent advances in acute kidney injury and its …

Acute kidney injury to chronic kidney disease transition

M Fiorentino, G Grandaliano, L Gesualdo… - Acute Kidney Injury …, 2018 - karger.com
Background: Acute kidney injury (AKI), even if followed by renal recovery, is a risk factor for
the future development of chronic kidney disease (CKD) and end-stage renal disease …

AKI: an increasingly recognized risk factor for CKD development and progression

JT Kurzhagen, S Dellepiane, V Cantaluppi… - Journal of nephrology, 2020 - Springer
Acute kidney injury (AKI) is an increasing health burden with high morbidity and mortality
rates worldwide. AKI is a risk factor for chronic kidney disease (CKD) development and …

[HTML][HTML] Novel insights into acute kidney injury–chronic kidney disease continuum and the role of renin–angiotensin system

YH Chou, TM Huang, TS Chu - Journal of the Formosan medical …, 2017 - Elsevier
Acute kidney injury (AKI) is an independent risk factor for chronic kidney disease (CKD). If
injury is mild, a repair process can be adaptive and lead to complete renal recovery …

Factors affecting the transition of acute kidney injury to chronic kidney disease: Potential mechanisms and future perspectives

J Ogbadu, G Singh, D Aggarwal - European Journal of Pharmacology, 2019 - Elsevier
Acute kidney injury (AKI) is defined as a rapid loss of kidney function characterised by
inflammation and cell death, ultimately leading to further functional and structural renal …

The acute kidney injury to chronic kidney disease transition: a potential opportunity to improve care in acute kidney injury

CE Palant, RL Amdur, LS Chawla - Acute Kidney Injury-From Diagnosis …, 2016 - karger.com
Recent controlled trials, epidemiological analyses and basic research studies offer a
comprehensive view of the short and long-term clinical repercussion of de novo acute …