Background: Chronic obstructive pulmonary disease (COPD) is associated with
cardiovascular disease. We investigated whether sleeping at altitude increases nocturnal …

Background COPD is associated with impaired pulmonary gas exchange and
cardiovascular disease. Travelling to high altitude may increase the risk of cardiac …

Introduction We investigated whether nocturnal oxygen therapy (NOT) mitigates the increase
of pulmonary artery pressure in patients during daytime with chronic obstructive pulmonary …

Abstract Study Objectives: Obstructive sleep apnea (OSA) promotes myocardial electrical
instability and may predispose to nocturnal sudden cardiac death. We evaluated whether …

Purpose Patients with chronic obstructive pulmonary disease (COPD) are particularly
vulnerable to hypoxia-induced autonomic dysregulation. Hypoxemia is marked during sleep …

Importance There are no established measures to prevent nocturnal breathing disturbances
and other altitude-related adverse health effects (ARAHEs) among lowlanders with chronic …

Altitude exposure induces hypoxaemia in patients with chronic obstructive pulmonary
disease (COPD), particularly during sleep. The present study tested the hypothesis in …

High‐altitude pulmonary hypertension (HAPH) is an altitude‐related illness associated with
hypoxaemia that may promote sympathetic excitation and prolongation of the QT interval …

Importance During mountain travel, patients with chronic obstructive pulmonary disease
(COPD) are at risk of experiencing severe hypoxemia, in particular, during sleep. Objective …

This trial evaluates whether nocturnal oxygen therapy (NOT) during a stay at 2048 m
improves altitude-induced exercise intolerance in lowlanders with chronic obstructive …