Neurobiology of estrogen status in deep craniofacial pain

DA Bereiter, K Okamoto - International Review of Neurobiology, 2011 - Elsevier
Pain in the temporomandibular joint (TMJ) region often occurs with no overt signs of injury or
inflammation. Although the etiology of TMJ-related pain may involve multiple factors, one …

The effects of estrogen on temporomandibular joint pain as influenced by trigeminal caudalis neurons

A Tashiro, DA Bereiter - Journal of Oral Science, 2020 - jstage.jst.go.jp
The signs and symptoms of persistent temporomandibular joint (TMJ)/muscle disorder
(TMJD) pain suggest the existence of a central neural dysfunction or a problem of pain …

Rapid estrogenic effects on TMJ-responsive brainstem neurons

A Tashiro, K Okamoto… - Journal of dental …, 2012 - journals.sagepub.com
Estrogen status is a risk factor for temporomandibular muscle and joint disorders (TMJD)
and other craniofacial pain conditions. The basis for estrogen modulation of pain is poorly …

Estrogen status and psychophysical stress modify temporomandibular joint input to medullary dorsal horn neurons in a lamina-specific manner in female rats

K Okamoto, R Thompson, A Katagiri, DA Bereiter - PAIN®, 2013 - Elsevier
Estrogen status and psychological stress contribute to the expression of several chronic pain
conditions including temporomandibular muscle and joint disorders (TMJD). Sensory …

Estrogen and inflammation increase the excitability of rat temporomandibular joint afferent neurons

NM Flake, DB Bonebreak… - Journal of …, 2005 - journals.physiology.org
Several painful conditions, including temporomandibular disorders (TMD), are more
prevalent and more severe in women than in men. Although the physiological basis for this …

Why look in the brain for answers to temporomandibular disorder pain?

E Sarlani, JD Greenspan - Cells Tissues Organs, 2005 - karger.com
Temporomandibular disorder (TMD) patients often exhibit widespread clinical pain, as well
as greater sensitivity to experimental pain than pain-free controls, suggesting a role of …

The influence of gender and sex steroids on craniofacial nociception

BE Cairns - Headache: The Journal of Head and Face Pain, 2007 - Wiley Online Library
Several pain conditions localized to the craniofacial region show a remarkable sex‐related
difference in their prevalence. These conditions include temporomandibular disorders and …

Chronic inflammation and estradiol interact through MAPK activation to affect TMJ nociceptive processing by trigeminal caudalis neurons

A Tashiro, K Okamoto, DA Bereiter - Neuroscience, 2009 - Elsevier
The mitogen-activated protein kinase/extracellular regulated kinase (MAPK/ERK) pathway
plays a key role in mediating estrogen actions in the brain and neuronal sensitization during …

Estrogen receptors localization in the spinal trigeminal nucleus: an immunohistochemical study in humans

F Fenzi, N Rizzzuto - European journal of pain, 2011 - Elsevier
There is increasing evidence for estrogenic modulation of neurotransmission within the
trigeminal pain pathway. It is also likely that the effects of estrogens may be influenced by …

GABAergic influence on temporomandibular joint-responsive spinomedullary neurons depends on estrogen status

A Tashiro, DA Bereiter, R Thompson, Y Nishida - Neuroscience, 2014 - Elsevier
Sensory input from the temporomandibular joint (TMJ) to neurons in superficial laminae at
the spinomedullary (Vc/C 1–2) region is strongly influenced by estrogen status. This study …