The latest evidence of erythropoietin in the treatment of glaucoma
TY Lin, YF Lai, YH Chen, DW Lu - International Journal of Molecular …, 2022 - mdpi.com
Erythropoietin (EPO) is a circulating hormone conventionally considered to be responsible
for erythropoiesis. In addition to facilitating red blood cell production, EPO has pluripotent …
for erythropoiesis. In addition to facilitating red blood cell production, EPO has pluripotent …
Erythropoietin in glaucoma: from mechanism to therapy
YF Lai, TY Lin, YH Chen, DW Lu - International Journal of Molecular …, 2023 - mdpi.com
Glaucoma can cause irreversible vision loss and is the second leading cause of blindness
worldwide. The disease mechanism is complex and various factors have been implicated in …
worldwide. The disease mechanism is complex and various factors have been implicated in …
Erythropoietin in optic neuropathies: current future strategies for optic nerve protection and repair
YF Lai, TY Lin, PK Ho, YH Chen, YC Huang… - International Journal of …, 2022 - mdpi.com
Erythropoietin (EPO) is known as a hormone for erythropoiesis in response to anemia and
hypoxia. However, the effect of EPO is not only limited to hematopoietic tissue. Several …
hypoxia. However, the effect of EPO is not only limited to hematopoietic tissue. Several …
Revisiting the role of erythropoietin for treatment of ocular disorders
SL Shirley Ding, SN Leow, R Munisvaradass, EH Koh… - Eye, 2016 - nature.com
Erythropoietin (EPO) is a glycoprotein hormone conventionally thought to be responsible
only in producing red blood cells in our body. However, with the discovery of the presence of …
only in producing red blood cells in our body. However, with the discovery of the presence of …
Up-regulated endogenous erythropoietin/erythropoietin receptor system and exogenous erythropoietin rescue retinal ganglion cells after chronic ocular hypertension
QL Fu, W Wu, H Wang, X Li, VWH Lee… - Cellular and molecular …, 2008 - Springer
Aims Recent studies have showed that erythropoietin (EPO) is a neuroprotectant for central
nerve system neurons in addition to being a hematopoietic cytokine in response to hypoxia …
nerve system neurons in addition to being a hematopoietic cytokine in response to hypoxia …
Use of erythropoietin in ophthalmology: A review
S Feizi, M Alemzadeh-Ansari, F Karimian… - Survey of …, 2022 - Elsevier
Erythropoietin (EPO) is a glycoprotein hormone that regulates hematopoiesis in the human
body. The presence of EPO and its receptors in different tissues indicates that this hormone …
body. The presence of EPO and its receptors in different tissues indicates that this hormone …
Erythropoietin: a candidate neuroprotective agent in the treatment of glaucoma
Glaucoma is a progressive optic neuropathy that is the leading cause of irreversible
blindness in the world. Although methods to lower intraocular pressure are the mainstay of …
blindness in the world. Although methods to lower intraocular pressure are the mainstay of …
Intraocular sustained release of EPO-R76E mitigates Glaucoma pathogenesis by activating the NRF2/ARE pathway
S Naguib, CR DeJulius, JR Backstrom, AA Haider… - Antioxidants, 2023 - mdpi.com
Erythropoietin (EPO) is neuroprotective in multiple models of neurodegenerative diseases,
including glaucoma. EPO-R76E retains the neuroprotective effects of EPO but diminishes …
including glaucoma. EPO-R76E retains the neuroprotective effects of EPO but diminishes …
Erythropoietin promotes survival of retinal ganglion cells in DBA/2J glaucoma mice
L Zhong, J Bradley, W Schubert… - … & visual science, 2007 - iovs.arvojournals.org
purpose. Retinal ganglion cell (RGC) loss occurs in response to increased intraocular
pressure (IOP) and/or retinal ischemia in glaucoma and leads to impairment of vision. This …
pressure (IOP) and/or retinal ischemia in glaucoma and leads to impairment of vision. This …
[HTML][HTML] Erythropoietin in ophthalmology: a literature review
Purpose To review the current literature on ocular application of erythropoietin (EPO).
Methods A comprehensive search was performed on Pubmed and Scopus databases. All …
Methods A comprehensive search was performed on Pubmed and Scopus databases. All …