Risk of hepatocellular carcinoma after HCV clearance by direct-acting antivirals treatment predictive factors and role of epigenetics

L Rinaldi, R Nevola, G Franci, A Perrella, G Corvino… - Cancers, 2020 - mdpi.com
Direct-acting antivirals (DAAs) induce a rapid virologic response (SVR) in up to 99% of
chronic hepatitis C patients. The role of SVR by DAAs on the incidence or recurrence of …

[HTML][HTML] Direct-acting antivirals and hepatocellular carcinoma in chronic hepatitis C: a few lights and many shadows

M Guarino, A Sessa, V Cossiga… - World journal of …, 2018 - ncbi.nlm.nih.gov
With the introduction of direct-acting antiviral agents (DAA), the rate of sustained virological
response (SVR) in the treatment of hepatitis C virus (HCV) has radically improved to over …

HCV eradication induced by direct-acting antiviral agents reduces the risk of hepatocellular carcinoma

GN Ioannou, PK Green, K Berry - Journal of hepatology, 2018 - Elsevier
Background & Aims It is unclear whether direct-acting antiviral (DAA) treatment-induced
sustained virologic response (SVR) reduces the risk of hepatocellular carcinoma (HCC) in …

[PDF][PDF] Long‐term risk of hepatocellular carcinoma in HCV patients treated with direct acting antiviral agents

F Kanwal, JR Kramer, SM Asch, Y Cao, L Li… - …, 2020 - Wiley Online Library
Sustained virologic response (SVR) after direct acting antiviral agents (DAAs) holds promise
for reducing hepatocellular cancer (HCC). DAAs have recently been available long enough …

Molecular mechanisms of hepatocarcinogenesis following sustained virological response in patients with chronic hepatitis C virus infection

CN Hayes, P Zhang, Y Zhang, K Chayama - Viruses, 2018 - mdpi.com
Despite the success of direct-acting antiviral (DAA) agents in treating chronic hepatitis C
virus (HCV) infection, the number of cases of HCV-related hepatocellular carcinoma (HCC) …

Risk of hepatocellular cancer in HCV patients treated with direct-acting antiviral agents

F Kanwal, J Kramer, SM Asch, M Chayanupatkul… - Gastroenterology, 2017 - Elsevier
Background and Aims The risk of hepatocellular cancer (HCC) after sustained virological
response (SVR) with direct-acting antivirals (DAA) is unclear. Our aim was to examine the …

Prediction model for hepatocellular carcinoma occurrence in patients with hepatitis C in the era of direct‐acting anti‐virals

Y Tahata, R Sakamori, R Yamada… - Alimentary …, 2021 - Wiley Online Library
Background Several factors associated with hepatocellular carcinoma (HCC) occurrence
after sustained virological response (SVR) in patients with hepatitis C have been reported …

Short‐term risk of hepatocellular carcinoma after hepatitis C virus eradication following direct‐acting anti‐viral treatment

E Ogawa, N Furusyo, H Nomura… - Alimentary …, 2018 - Wiley Online Library
Background With the development of direct‐acting anti‐virals (DAA s), almost all patients
with chronic hepatitis C virus (HCV) infection can achieve sustained viral response (SVR) …

Direct-acting antiviral agents do not increase the incidence of hepatocellular carcinoma development: a prospective, multicenter study

T Ide, H Koga, M Nakano, S Hashimoto… - Hepatology …, 2019 - Springer
Background While achieving sustained virological response (SVR) following interferon-
based or direct-acting antiviral agent (DAA) treatments reduces the incidence of …

[HTML][HTML] Occurrence and recurrence of hepatocellular carcinoma after successful direct-acting antiviral therapy for patients with chronic hepatitis C virus infection

S Grandhe, CT Frenette - Gastroenterology & hepatology, 2017 - ncbi.nlm.nih.gov
Chronic hepatitis C virus (HCV) infection has generally been associated with a slightly
increased risk of developing hepatocellular carcinoma (HCC). For the past several decades …