Hundreds of thousands of people die each year as a result of sudden cardiac death, and
many are due to heart rhythm disorders. One of the major causes of these arrhythmic events …

Brugada syndrome (BrS) is an inherited and rare cardiac arrhythmogenic disease
associated with an increased risk of ventricular fibrillation and sudden cardiac death …

Abstract Background: Brugada syndrome (BrS), a disorder associated with characteristic
electrocardiogram precordial ST-segment elevation, predisposes afflicted patients to …

Brugada syndrome (BrS) is an inherited cardiac arrhythmia that predisposes to ventricular
fibrillation and sudden cardiac death. It originates from oligogenic alterations that affect …

Brugada syndrome predisposes to sudden death due to disruption of normal cardiac ion
channel function, yet our understanding of the underlying cellular mechanisms is …

Brugada syndrome (BrS) is a rare, inherited arrhythmia with high risk of sudden cardiac
death. To evaluate the molecular convergence of clinically relevant mutations and to identify …

Brugada syndrome (BrS) is a rare cardiac rhythm disorder associated with sudden cardiac
death. Mutations in the sodium channel gene SCN5A are found in~ 20% of cases while …

Brugada syndrome is an inherited cardiac arrhythmia disorder that is mainly associated with
mutations of the cardiac voltage-gated sodium channel alpha subunit 5 (SCN5A) gene. The …

Brugada syndrome is an inherited, rare cardiac arrhythmogenic disease, associated with
sudden cardiac death. It accounts for up to 20% of sudden deaths in patients without …

Abstract Aims The Brugada syndrome (BrS) is an inherited cardiac disorder predisposing to
ventricular arrhythmias. Despite considerable efforts, its genetic basis and cellular …