Biomaterials releasing drug responsively to promote wound healing via regulation of pathological microenvironment

H Li, B Li, D Lv, W Li, Y Lu, G Luo - Advanced Drug Delivery Reviews, 2023 - Elsevier
Wound healing is characterized by complex, orchestrated, spatiotemporal dynamic
processes. Recent findings demonstrated suitable local microenvironments were …

Instructive microenvironments in skin wound healing: Biomaterials as signal releasing platforms

O Castano, S Pérez-Amodio… - Advanced drug delivery …, 2018 - Elsevier
Skin wound healing aims to repair and restore tissue through a multistage process that
involves different cells and signalling molecules that regulate the cellular response and the …

Bioactive materials promote wound healing through modulation of cell behaviors

R Li, K Liu, X Huang, D Li, J Ding, B Liu… - Advanced …, 2022 - Wiley Online Library
Skin wound repair is a multistage process involving multiple cellular and molecular
interactions, which modulate the cell behaviors and dynamic remodeling of extracellular …

Spatiotemporal delivery of bioactive molecules for wound healing using stimuli-responsive biomaterials

N Oliva, BD Almquist - Advanced drug delivery reviews, 2020 - Elsevier
Wound repair is a fascinatingly complex process, with overlapping events in both space and
time needed to pave a pathway to successful healing. This additional complexity presents …

Drug delivery systems and materials for wound healing applications

S Saghazadeh, C Rinoldi, M Schot, SS Kashaf… - Advanced drug delivery …, 2018 - Elsevier
Chronic, non-healing wounds place a significant burden on patients and healthcare
systems, resulting in impaired mobility, limb amputation, or even death. Chronic wounds …

Leveraging the advancements in functional biomaterials and scaffold fabrication technologies for chronic wound healing applications

AA Zahid, A Chakraborty, Y Shamiya, SP Ravi… - Materials …, 2022 - pubs.rsc.org
Exploring new avenues for clinical management of chronic wounds holds the key to
eliminating socioeconomic burdens and health-related concerns associated with this silent …

Rational design of intelligent and multifunctional dressing to promote acute/chronic wound healing

L Zhou, T Min, X Bian, Y Dong, P Zhang… - ACS Applied Bio …, 2022 - ACS Publications
Currently, the clinic's treatment of acute/chronic wounds is still unsatisfactory due to the lack
of functional and appropriate wound dressings. Intelligent and multifunctional dressings are …

Multimodal bioactive material approaches for wound healing

S Mandla, L Davenport Huyer, M Radisic - APL bioengineering, 2018 - pubs.aip.org
Wound healing is a highly complex process of tissue repair that relies on the synergistic
effect of a number of different cells, cytokines, enzymes, and growth factors. A deregulation …

Advanced biomaterials for regulating polarization of macrophages in wound healing

J Mao, L Chen, Z Cai, S Qian, Z Liu… - Advanced Functional …, 2022 - Wiley Online Library
Macrophage immunotherapy is an emerging treatment strategy that modulates the immune
system to promote wound healing. The functionality and regeneration of tissue depend on …

Drug therapies and delivery mechanisms to treat perturbed skin wound healing

JS Chin, L Madden, SY Chew, DL Becker - Advanced Drug Delivery …, 2019 - Elsevier
Acute wound healing is an orderly process of four overlapping events: haemostasis,
inflammation, proliferation and remodelling. A drug delivery system with a temporal control …