High blood pressure is a major contributor to the global burden of disease and discovering
novel causal pathways of blood pressure regulation has been challenging. We tested blood …

Objective: To identify novel and confirm previously reported metabolites associated with
SBP, DBP, and hypertension in a biracial sample of Bogalusa Heart Study (BHS) …

Objective In order to search for metabolic biomarkers of antihypertensive drug
responsiveness, we measured> 600 biochemicals in plasma samples of subjects …

Objective: The pathophysiology of hypertension remains incompletely understood. We
investigated associations of circulating metabolites with longitudinal blood pressure (BP) …

Background Hypertension and dyslipidemia are two main risk factors for cardiovascular
diseases (CVD). Moreover, their coexistence predisposes individuals to a considerably …

We aimed to explore novel small metabolites that associated with hypertension risk in a
population‐based nested case‐control study. Among 460 individuals with optimal blood …

Metabolomics is a promising tool to gain new insights into early metabolic alterations
preceding the development of hypertension in humans. We therefore aimed to identify …

Abstract Purpose of the Review This review presents the analytical techniques, processing
and analytical steps used in metabolomics phenotyping studies, as well as the main results …

There is concern about the increasing burden of essential hypertension in urban–dwelling
black South Africans, especially males. Several studies have investigated urbanization and …

Early detection of pathogenesis through biomarkers holds the key to controlling
hypertension and preventing cardiovascular complications. Metabolomics profiling acts as a …