Placental leptin in normal, diabetic and fetal growth-retarded pregnancies

RG Lea, D Howe, LT Hannah… - Molecular human …, 2000 - academic.oup.com
Leptin expression in third trimester placenta (p) and leptin concentrations in umbilical cord
blood (cb) were investigated in normal pregnancies [n= 10 (p), 31 (cb)] and abnormal …

Leptin receptor in human term placenta: in situ hybridization and immunohistochemical localization

J Bodner, CF Ebenbichler, HJ Wolf, E Müller-Holzner… - Placenta, 1999 - Elsevier
In the present study, we investigated the expression and localization of leptin receptors in
human term placentae. On human term placenta tissue slices, digoxigenin-UTP labelled …

Placental leptin

CJ Ashworth, N Hoggard, L Thomas… - Reviews of …, 2000 - rep.bioscientifica.com
Placental tissues from humans, rodents and farm animals contain leptin and its receptor.
Leptin produced by the human placenta has the same size, charge and immunoreactivity as …

Expression of placental leptin and leptin receptor transcripts in early pregnancy and at term

MC Henson, KF Swan, JS O'NEIL - Obstetrics & Gynecology, 1998 - journals.lww.com
Objective: To demonstrate the expression of messenger RNA (mRNA) transcripts for
placental leptin and leptin receptor in early gestation and at term, to quantitate …

Synthesis of leptin in human placenta

R Señarís, T Garcia-Caballero, X Casabiell… - …, 1997 - academic.oup.com
Gender-based differences in serum leptin levels have been reported in umbilical cord blood,
and leptin has been detected in human amniotic fluid. In order to understand if leptin may be …

Placental leptin receptor isoforms in normal and pathological pregnancies

J Challier, M Galtier, T Bintein, A Cortez, J Lepercq… - Placenta, 2003 - Elsevier
Alternate mRNA splicing of human leptin receptor generates four membrane isoforms with
different C-terminal sequences. They differ by the length of their intracellular domain which …

Serum leptin concentrations and expression of leptin transcripts in placental trophoblast with advancing baboon pregnancy

MC Henson, VD Castracane, JS O'Neil… - The Journal of …, 1999 - academic.oup.com
Leptin is a polypeptide hormone originally thought to be produced exclusively by
adipocytes. Recently, however, both leptin messenger ribonucleic acid (mRNA) and leptin …

Human umbilical cord and fetal membranes co-express leptin and its receptor genes

F Akerman, ZM Lei, CV Rao - Gynecological endocrinology, 2002 - Taylor & Francis
Leptin, protein product of the ob gene, not only regulates food intake and energy
expenditure but also has a number of other actions in the body. Leptin actions are mediated …

The placenta is not the main source of leptin production in pregnant rat: gestational profile of leptin in plasma and adipose tissues

M Kawai, M Yamaguchi, T Murakami, K Shima… - Biochemical and …, 1997 - Elsevier
The gestational profiles of leptin in plasma, adipose tissue and placenta were investigated in
rats. Leptin in plasma and the adipose tissue of the maternal compartment increased as …

Leptin Production and Release in the Dually in VitroPerfused Human Placenta

K Linnemann, A Malek, R Sager… - The Journal of …, 2000 - academic.oup.com
There is clear evidence that the placenta produces leptin. However, it is still unclear to what
extent leptin is released into the maternal and the fetal circulation. The aim of our study was …