Prostanoid EP1 receptor as the target of (−)-epigallocatechin-3-gallate in suppressing hepatocellular carcinoma cells in vitro

J Jin, Y Chang, W Wei, Y He, S Hu, D Wang… - Acta Pharmacologica …, 2012 - nature.com
Aim: To investigate the effects of (−)-epigallocatechin-3-gallate (EGCG), an active compound
in green tea, on prostaglandin E 2 (PGE 2)-induced proliferation and migration, and the …

Synergetic effect of EP1 receptor antagonist and (-)-Epigallocatechin-3-gallate in hepatocellular carcinoma

H Yang, M Wang, H Sun, S Zhu, J Jin - Pharmacology, 2019 - karger.com
Abstract Epigallocatechin-3-gallate (EGCG), the principal catechin of green tea, modulates
different molecular mechanisms underlying hepatocellular carcinoma (HCC). Accumulating …

Involvement of the prostaglandin E receptor EP2 in paeoniflorin-induced human hepatoma cell apoptosis

S Hu, W Sun, W Wei, D Wang, J Jin, J Wu… - Anti-Cancer …, 2013 - journals.lww.com
Abstract Prostaglandin E 2 (PGE 2) has been shown to play an important role in tumor
development and progression. PGE 2 mediates its biological activity by binding any one of …

Epigallocatechin-3-gallate inhibits proliferation and migration of human colon cancer SW620 cells in vitro

F Zhou, H Zhou, T Wang, Y Mu, B Wu, D Guo… - Acta Pharmacologica …, 2012 - nature.com
Aim: Epigallocatechin-3-gallate (EGCG) is the major polyphenolic constituent in green tea.
The aim of this study is to investigate the effects of EGCG on proliferation and migration of …

Green tea polyphenol epigallocatechin-3-gallate inhibits thrombin-induced hepatocellular carcinoma cell invasion and p42/p44-MAPKinase activation

R Kaufmann, P Henklein, P Henklein… - Oncology …, 2009 - spandidos-publications.com
Thrombin has been recently demonstrated to promote hepatocellular carcinoma (HCC) cell
migration by activation of the proteinase-activated receptor (PAR) subtypes PAR1 and PAR4 …

Green tea epigallocatechin-3-gallate inhibits microsomal prostaglandin E2 synthase-1

A Koeberle, J Bauer, M Verhoff, M Hoffmann… - Biochemical and …, 2009 - Elsevier
Prostaglandin (PG) E2 is a critical lipid mediator connecting chronic inflammation to cancer.
The anti-carcinogenic epigallocatechin-3-gallate (EGCG) from green tea (Camellia sinensis) …

Epigallocatechin-3-gallate induces apoptosis in human hepatocellular carcinoma cells

XL Chen, Q Wang, LQ Cao, XH Huang, XH Fu… - Zhonghua yi xue za …, 2008 - europepmc.org
Objective To investigate the effects of epigallocatechin-3-gallate (EGCG) on human
hepatocellular carcinoma (HCC) cells and mechanism thereof. Method Human HCC cells of …

[HTML][HTML] Anti-metastatic and differential effects on protein expression of epigallocatechin-3-gallate in HCCLM6 hepatocellular carcinoma cells

Y Zhang, L Owusu, W Duan… - International …, 2013 - spandidos-publications.com
Hepatocellular carcinoma (HCC) is the fifth most common cancer worldwide and the third
highest cause of cancer-related mortality in humans. Epigallocatechin-3-gallate (EGCG) has …

Molecular mechanism of epigallocatechin-3-gallate in human esophageal squamous cell carcinoma in vitro and in vivo

L Liu, L Hou, S Gu, X Zuo, D Meng… - Oncology …, 2015 - spandidos-publications.com
Abstract Epigallocatechin-3-gallate (EGCG), the major polyphenol of green tea, has been
shown to inhibit proliferation in various types of tumors. However, few studies concerning the …

The epigallocatechin gallate derivative Y6 inhibits human hepatocellular carcinoma by inhibiting angiogenesis in MAPK/ERK1/2 and PI3K/AKT/HIF-1α/VEGF …

ZH Liao, HQ Zhu, YY Chen, RL Chen, LX Fu… - Journal of …, 2020 - Elsevier
Ethnopharmacological relevance Hypervascularity has been considered as one of the major
features of many solid tumors. Green tea is one of the commonly drink resources in China …